Mesalazine in the Treatment of Extensive Alopecia Areata: A New Therapeutic Option?
January 2018
in “
International Journal of Trichology
”
Studysummary In this study, researchers retrospectively analyzed five children with extensive and refractory alopecia areata treated with mesalazine, observing complete hair regrowth in all patients without side effects, suggesting potential benefits of this treatment combination, though controlled studies are needed for confirmation. Our plain-language summary of this paper — not a Tressless recommendation.
The study retrospectively analyzed five pediatric patients (aged 2–17 years) with extensive and refractory alopecia areata treated with mesalazine, with or without oral prednisolone and topical betamethasone/minoxidil. All patients experienced complete hair regrowth without abnormal lab results or drug side effects. The findings suggested that mesalazine could be an effective adjunctive therapy for severe alopecia areata, potentially reducing the need for prolonged oral corticosteroid use and minimizing relapses. However, controlled studies were recommended to confirm these results.
