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Finding new uses for existing drugs is promising and can lead to safer, more effective medicines.

Researchers found potential urine markers for polycystic ovary syndrome, including testosterone-glucuronide and 11α-hydroxyprogesterone, which may help diagnose the condition.

Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.

Liposomes could improve how skin care products work but are costly and not very stable.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Hirsutism can lower a woman's quality of life, causing emotional distress and affecting social and work opportunities.

New hair follicle-targeting treatments show promise for hair disorders but need more research on safety and effectiveness.

Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

The severity of symptoms in nonclassical congenital adrenal hyperplasia is not determined by CYP21A2 gene variations.

The document concludes that there are various causes and treatments for hair loss, with hair transplantation being a notable option.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Some plants with flavonoids may help treat hair loss and promote hair growth.

Acne treatment varies, with topical and systemic therapies effective, and more research needed on treatment order and long-term effects.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.

Adding platelet-rich plasma improves hair density and thickness in androgenetic alopecia.

Aldactone effectively reduces hair thickness in women with excessive hair growth, both alone and with other treatments.

Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.

Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Finasteride effectively treats male pattern baldness, improving hair growth and density.

Testosterone may help increase sexual events for women with low libido due to antidepressants.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.

A woman's hair loss from graft versus host disease helps understand similar hair loss conditions.