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Stem-cell therapy shows promise for skin conditions but needs more research.

Pigs without the Hairless gene showed skin and thymus changes, useful for studying human hair disorders.

B2m-free HLA variants may be a new class of HLA important in immune responses and diseases.

Sheep with chronic Sarcoptes scabiei dermatitis have altered keratin expression in their skin.

New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

Chitosan hydrogels are promising for repairing blood vessels but need improvements in strength and compatibility.

Understanding how Regulatory T Cells work could help create treatments for certain skin diseases and cancers.

Biologic agents can be effective for rheumatic diseases but have risks like infections and require careful monitoring and patient information.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.

The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.

Alopecia areata is an autoimmune hair loss condition treated with corticosteroids, and histologic confirmation is the best diagnosis method.

Researchers found a good way to isolate hair follicle stem cells from newborn goats for further study.

Permanent hair dye mixtures can irritate and damage the skin.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

Some alternative therapies for vitiligo show promise but need more research.

The book details skin conditions in older adults, their link to mental health, cancer treatment importance, hair loss remedies, and managing autoimmune and itchy skin.

Hair follicles help skin immune recovery after UVB exposure.

BIVV009 is a safe treatment for bullous pemphigoid that reduces C3 deposition without harmful side effects.

As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.

Stem cells from hair follicles in a special gel show strong potential for bone regeneration.