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The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.

Anti-androgens can help treat tough skin conditions like severe acne and excessive hair growth.

Androgenetic alopecia linked to COVID-19 severity; drugs reducing androgen receptor activation may help.

A certain genetic variant in the androgen receptor may predict the severity of COVID-19 in men.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

COVID-19 may worsen with androgens; anti-androgen drugs could help.

Hair ages due to various factors and treatments like minoxidil and finasteride can help, but more research and better public awareness are needed.

Clascoterone is a new, effective, and safe acne treatment without systemic side effects.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.

Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.

Hormonal therapy like cyproterone acetate and spironolactone may help female hair loss, but more research is needed, especially for pre-menopausal women.

FPHL causes hair loss in women due to genetics and hormones; minoxidil and anti-androgens are treatments, and early intervention is advised.

Excessive body hair in women can be caused by various conditions and treated with medication like Diane® 35 or androgen blockers.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

Hormonal therapies like cyproterone acetate and spironolactone may help some women with hair loss, but finasteride 1mg is not useful, and the effectiveness of other treatments is still unclear.

The document says that hair loss in women is often due to androgenic alopecia, similar to male baldness, and that hirsutism is treated with hormonal and cosmetic methods.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Severe male balding may increase the risk of serious COVID-19, and treatments that reduce androgens or block a specific enzyme might help protect these individuals.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

The document suggests various treatments for PCOS, including medication for menstrual issues, insulin resistance, and excess hair, as well as fertility treatments, while highlighting the need for personalized care and lifestyle changes.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Menopause can cause skin issues, and seeing a dermatologist helps.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

The chapter explains the causes of excessive hair growth and masculinization in women and how to measure hormone levels related to these conditions.