research Severity of Alopecia Predicts Coronary Changes and Arterial Stiffness in Untreated Hypertensive Men
Men with severe early-onset baldness may have worse heart artery function and stiffer arteries if they have high blood pressure.
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research The Rotterdam Study: 2018 Update on Objectives, Design, and Main Results
The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.
research Physiopathological Role of the Enzymatic Complex 5α-Reductase and 3α/β-Hydroxysteroid Oxidoreductase in the Generation of Progesterone and Testosterone Neuroactive Metabolites
The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
research Main Plenary Sessions: Summaries of Papers
UK medical students lack dermatology education, liver biopsy patients with risk factors show more fibrosis, and certain fungi resist drugs due to melanin; genetics may influence female hair loss.
research Novel Mutations of the ABCA12, KRT1 and ST14 Genes in Three Unrelated Newborns Showing Congenital Ichthyosis
New genetic mutations linked to rare skin disorders were found in three newborns.
research Clinical Trials and Hair Loss
Many treatments for hair loss show potential, but more testing is needed to confirm their effectiveness. Only minoxidil for women and minoxidil and finasteride for men are FDA approved.
research Case Report: Alopecia Areata Universalis Successfully Treated with Baricitinib
Baricitinib successfully treated severe hair loss.
research Analysis of Androgen Receptor Expression and Activity in the Mouse Brain
Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.
research Uses of Spironolactone as an Antiandrogenic Drug
Spironolactone is effective and safe for treating hair loss, excessive hair growth, and acne.
research Forensics in Dermatology: Part II
Dermatologists play a key role in identifying and documenting signs of abuse and injury for forensic investigations.
research Neuroendocrine Controls of Keratin Expression in Human Skin
Neurohormones help control skin health and could treat skin disorders.
research Effects of Altering Allopregnanolone Levels During Critical Neurodevelopmental Periods on Alcohol Consumption Vulnerability
Early NAS level changes affect alcohol consumption vulnerability.
research The Nocebo Effect: A Clinician's Guide
Negative expectations can cause adverse effects in patients even without active treatment, and managing this nocebo effect involves better communication and patient-clinician relationships.
research Allopregnanolone Mediates the Exacerbation of Tourette-Like Responses by Acute Stress in Mouse Models
Stress worsens Tourette symptoms by increasing allopregnanolone levels.
research Cutaneous and Mucosal Lichen Planus: A Comprehensive Review of Clinical Subtypes, Risk Factors, Diagnosis, and Prognosis
Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.
research Advances in Knowledge of Androgens: How Intentional and Accidental Neurosteroid Changes Inform Us of Their Action and Role
Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.
research Was It Gold That Shone? Platelet-Rich Plasma Applications, Outcomes, and Safety Considerations
Platelet-rich plasma therapy may have benefits and is generally safe, but more research is needed to confirm its effectiveness and safety.
research Pictorial Essay on Hair Loss Due to Head Bones Displacement
The essay suggests hair loss might be caused by changes in skull bones.
research Dental Management in a 7-Year-Old Child with Ichthyosis Vulgaris: A Rare Case Report
Dentists should start preventive treatments early for children with Ichthyosis Vulgaris to avoid dental problems.
research Innovative Reports on the Effects of Anabolic Androgenic Steroid Abuse - How to Lose Your Mind for the Love of Sport
Abusing steroids can damage your heart, muscles, reproductive system, liver, skin, and brain, and may increase the risk of Alzheimer's disease.
research Case Report: Alopecia Areata and Cannabis Use
A girl with severe hair loss saw hair regrowth after using cannabis.
research Congenital Triangular Alopecia: A Case of Effective Response with 5% Topical Minoxidil in a Male Adolescent
5% topical minoxidil effectively treated a boy's congenital triangular alopecia without side effects.
research Ectodermal Dysplasia: Otolaryngologic Manifestations and Management
Ectodermal dysplasia causes various symptoms and early treatment is important for eye, dental, and skin issues.
research Scalp Dysesthesia Related to Cervical Spine Disease
Most women with weird scalp feelings had neck spine problems, and some got better with gabapentin treatment.
research Molecular Basis of Androgen Action on Human Sexual Desire
Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.
research The 5α-Reductase Inhibitor Finasteride Exerts Neuroprotection Against Ischemic Brain Injury in Aged Male Rats
Finasteride helps protect brain in old male rats.
research Relationship Between Androgenic Alopecia and White Matter Hyperintensities in Apparently Healthy Subjects
Hair loss can indicate brain aging and potential small vessel disease, but more research is needed to understand the clinical impact.
research Consequences of Steroid-5α-Reductase Deficiency and Inhibition in Vertebrates
Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
research Tumor Regression Predicts Higher Risk of Sentinel Node Involvement in Thin Cutaneous Melanomas
Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.
research Ichthyosis Follicularis, Alopecia, and Photophobia Syndrome in a Saudi Child: A Case Report
An 8-year-old Saudi boy was diagnosed with a rare genetic disorder causing hair loss, skin issues, and light sensitivity.