research Regulation of Involucrin Gene Expression
Involucrin gene expression is controlled by specific proteins and signaling pathways.
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research Phase I Study of the Hedgehog Pathway Inhibitor IPI-926 in Adult Patients with Solid Tumors
The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.
research The Disintegrin/Metalloproteinase Adam10 Is Essential for Epidermal Integrity and Notch-Mediated Signaling
Adam10 enzyme is crucial for healthy skin and proper Notch signaling.
research Penetration Enhancer-Containing Vesicles as Carriers for Cutaneous Delivery of Minoxidil
PEVs improve minoxidil skin penetration, increasing hair growth.
research Endocannabinoids Limit Excessive Mast Cell Maturation And Activation In Human Skin
Endocannabinoids help control mast cell activity in human skin.
research Neurosteroidogenesis Today: Novel Targets for Neuroactive Steroid Synthesis and Action and Their Relevance for Translational Research
New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.
research Maternal Influence on Child HPA Axis: A Prospective Study of Cortisol Levels in Hair
Maternal stress during pregnancy affects a child's stress levels.
research Nanoparticle-Based Targeting of Vaccine Compounds to Skin Antigen-Presenting Cells by Hair Follicles and Their Transport in Mice
Nanoparticles can deliver vaccines through hair follicles, triggering immune responses and providing protection.
research Dental Cell Type Atlas Reveals Stem and Differentiated Cell Types in Mouse and Human Teeth
The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.
research Nocturnal Eczema: Review of Sleep and Circadian Rhythms in Children with Atopic Dermatitis and Future Research Directions
Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.
research Follicular Targeting: A Promising Tool in Selective Dermatotherapy
Targeting hair follicles can improve skin treatments and reduce side effects.
research The Human Hair: From Anatomy to Physiology
The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.
research Testosterone, Dihydrotestosterone, and Incident Cardiovascular Disease and Mortality in the Cardiovascular Health Study
DHT may increase the risk of heart disease and death in elderly men.
research The Management of Very Low-Calorie Ketogenic Diet in Obesity Outpatient Clinic: A Practical Guide
A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.
research Human Hair Follicle: Reservoir Function and Selective Targeting
The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.
research Neutrophil Gelatinase-Associated Lipocalin Is a Marker for Dysregulated Keratinocyte Differentiation in Human Skin
NGAL indicates abnormal skin cell differentiation.
research Worldwide Diversity of Hair Curliness: A New Method of Assessment
A new method accurately classifies hair types, showing global hair diversity.
research Shape Variability and Classification of Human Hair: A Worldwide Approach
Human hair can be classified into eight types based on physical features, not ethnicity.
research Cloning of Wrinkle-Free, a Previously Uncharacterized Mouse Mutation, Reveals Crucial Roles for Fatty Acid Transport Protein 4 in Skin and Hair Development
Fatty acid transport protein 4 is essential for skin and hair development.
research Polycystic Ovary Syndrome: Update on Diagnosis and Treatment
The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.
research A Novel Point Mutation in the Ligand-Binding Domain of the Human Glucocorticoid Receptor Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus in Conferring Transactivational Activity
A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.
research Trichoscopy of Alopecia Areata: An Update
Trichoscopy helps diagnose and monitor alopecia areata by looking at a combination of specific hair and scalp features.
research Health And Fertility In World Health Organization Group 2 Anovulatory Women
Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.
research Synthesis and Structure–Activity Relationships of the First Ferrocenyl-Aryl-Hydantoin Derivatives of the Nonsteroidal Antiandrogen Nilutamide
Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.
research Endocrine Intervention for Transsexuals
Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.
research Clinical Severity Does Not Reliably Predict Quality of Life in Women With Alopecia Areata, Telogen Effluvium, or Androgenic Alopecia
How bad a woman's hair loss is doesn't always match how it affects her happiness and daily life.
research Depression, Anxiety, and Perceived Stress in Women With and Without PCOS: A Community-Based Study
Women with PCOS are more likely to suffer from depression, anxiety, and stress.
research Myocardial NF-κB Activation Is Essential for Zebrafish Heart Regeneration
NF-κB is crucial for zebrafish heart repair, affecting heart cell growth and repair processes.
research Liposomes And Niosomes As Potential Carriers For Dermal Delivery Of Minoxidil
Liposomes better deliver minoxidil for hair loss treatment than niosomes.
research Activation of Nrf2 in Keratinocytes Causes Chloracne-Like Skin Disease in Mice
Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.