Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study reported that postmenopausal patients with advanced breast cancer prioritize quality of life, overall survival, and progression-free survival over therapy-related side effects when considering cancer treatment decisions.

In this prospective phase II clinical trial, researchers are investigating whether adding dutasteride to combined androgen blockade can improve the response rate and clinical outcomes for patients with androgen receptor-positive recurrent or metastatic salivary duct carcinoma.

Vascular patterns in dermoscopy help tell apart malignant and benign skin tumors.

This case report describes a rare instance of thymoma associated with alopecia areata in a 60-year-old woman who had no signs of myasthenia gravis, highlighting the need for thoracic surgeons to consider alopecia in such cases due to its impact on quality of life.

This case report describes a 55-year-old woman with alopecia areata whose condition improved rapidly and did not recur after the surgical resection of a thymoma, suggesting a potential immunological link between alopecia areata and thymoma that warrants further investigation.

In this study, the researchers observed significant down-regulation of Transglutaminase-3 expression in esophageal cancer tissues compared to normal tissues, suggesting its alteration is a common event in esophageal cancer development.

This study found that the most significant negative emotional responses among cancer patients during consultations were related to treatment delays and the possibility of hair loss.

This case report details a 73-year-old woman with significant hirsutism and hair loss linked to a rare ovarian Leydig cell tumor, which was resolved by bilateral salpingo-oophorectomy, normalizing her testosterone levels and addressing her symptoms.

In a randomized clinical trial, Robinson et al found that patients with melanoma and their partners could effectively perform skin self-examinations after participating in a 30-minute structured skills training, potentially aiding early detection of additional melanomas.

This review discusses nonsteroidal selective androgen receptor modulators and their potential therapeutic applications but reports no new clinical findings.

This review critically evaluates the evidence for SARMs' tissue selectivity and suggests their clinical benefits over traditional androgens are not yet well-supported by robust evidence, underscoring the need for further head-to-head trials.

This letter argues that the lymphangitis reported from using cantharidin on warts is instead a case of aseptic necrosis common to other aggressive wart treatments.

This review discusses the management of adverse events associated with sacituzumab govitecan use in real-world settings and provides no new clinical results; it emphasizes practical strategies for clinicians treating breast cancer patients.

This case report describes a rare instance of pityriasis amiantacea and cutis verticis gyrata occurring in a 32-year-old man with B-cell acute lymphoblastic leukemia, highlighting this previously unreported dermatological manifestation and stressing the importance of clinical awareness.

This case report identifies a novel AR gene mutation in an adolescent with primary amenorrhea, suggesting that CAIS should be considered when evaluating patients with a female phenotype and breast development.

In this study, early-onset androgenetic alopecia patients showed a higher prevalence of metabolic syndrome and carotid atheromatosis compared to a control group, suggesting the need for cardiovascular risk screening in this population.

In this case study, a 65-year-old male with hepatocellular carcinoma treated with the PD-1 inhibitor Sintilimab developed alopecia universalis alongside significant tumor regression and complete remission, highlighting a rare immune-related adverse event with effective anti-tumor outcomes.

In this Phase II study, BAY 43–9006, taken orally for renal cell carcinoma, stabilized disease in 30% of patients, with 40% responding positively, although the targets remain unclear.

This paper reviews adrenocortical carcinoma, discussing its prevalence, symptoms, diagnosis, and treatment options, but reports no new clinical results.

This correspondence reports that using cantharidin on warts can result in lymphangitis, and dermatologists should consider all potential complications of treatments.

In this review, the authors detailed various dermatologic adverse events associated with aromatase inhibitors in postmenopausal women and discussed strategies to potentially prevent these events, aiming to minimize interruptions in breast cancer treatment.

This study observed that MIRV improved gastrointestinal symptoms and other quality of life measures in patients with platinum-resistant ovarian cancer compared to chemotherapy.

This case report describes digital gangrene as a rare primary manifestation of late-onset systemic lupus erythematosus in a 56-year-old man, with marked lesion improvement following rituximab treatment.

In liver cancer cells, this study found that upregulating hsa_circ_0002980 inhibits cell proliferation, metastasis, and EMT by modulating the miR-1303/CADM2 axis, suggesting it as a potential therapeutic target.

This study found that the novel anti-HER2 antibody RC48 demonstrated promising activity and manageable safety in patients with HER2-overexpressing, advanced gastric or gastroesophageal junction cancer after at least two prior chemotherapy lines.

This case report details a 54-year-old woman with metastatic non-small-cell lung cancer who experienced severe hair loss and exanthematous drug eruption, potentially linked to erlotinib hypersensitivity.

This report describes an extremely rare case of arteriovenous fistula appearing after hair restoration surgery, observed in just one instance.

This study found that GNAQQ209L expression in mouse melanocytes led to reduced survival in the interfollicular epidermis due to paracrine signaling, while GNAQQ209L boosted survival in a different microenvironment.

A woman with Parry-Romberg syndrome developed new curly hair on one side of her scalp, a condition not previously linked to the syndrome.