June 1995 in “International Journal of Gynecology & Obstetrics” Long-term use of oral contraceptives, especially starting before age 20, may increase the risk of early-onset breast cancer.
947 citations,
February 2004 in “The Journal of Clinical Endocrinology and Metabolism” Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.
89 citations,
November 2014 in “International Journal of Nanomedicine” Using nanostructured lipid carriers to deliver spironolactone could improve treatment for hair loss.
81 citations,
July 2012 in “Translational Psychiatry” Memantine may slightly improve memory in people with Down syndrome, but more research is needed.
73 citations,
January 2013 in “Annals of Dermatology” People with hair loss, especially those with certain types, have lower zinc levels, and zinc supplements might help.
60 citations,
May 2018 in “Indian Journal of Psychological Medicine” Women with PCOS often experience anxiety, depression, and a lower quality of life.
53 citations,
June 2017 in “Skin appendage disorders” PRP treatment helps hair growth in most cases, but more research needed.
50 citations,
October 2009 in “Clinical Endocrinology” Hair loss in young men linked to higher risk of insulin resistance and metabolic issues.
49 citations,
February 2009 in “Maturitas” Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.
41 citations,
January 2020 in “Journal of Ovarian Research” Quercetin may help with PCOS symptoms, but more research is needed.
40 citations,
December 2016 in “Journal of Ovarian Research” Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.
40 citations,
May 1999 in “Journal of The European Academy of Dermatology and Venereology” Treat hair loss with finasteride, minoxidil, or surgery; consider side effects and severity.
37 citations,
April 2008 in “The Cochrane library” 5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.
36 citations,
September 2018 in “American Journal of Clinical Dermatology” Combination of 0.25% finasteride and 3% minoxidil works better than just 3% minoxidil for increasing hair thickness in women.
36 citations,
August 2011 in “Experimental Dermatology” Eccrine sweat gland's clear cells likely cause excessive sweating in hyperhidrosis.
35 citations,
April 2013 in “Sexual medicine reviews” 5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.
35 citations,
May 2012 in “Cochrane Database of Systematic Reviews” Minoxidil effectively treats female pattern hair loss.
32 citations,
April 1999 in “Expert Opinion on Investigational Drugs” Finasteride effectively treats male hair loss, improving growth and density.
27 citations,
May 2010 in “Dermatologic Clinics” Zinc can be a helpful secondary treatment for certain skin conditions, but more research is needed to guide its use.
25 citations,
July 2017 in “Archives of Dermatological Research” Herbal products might promote hair growth with fewer side effects, but more research is needed to confirm their safety and effectiveness.
23 citations,
August 2018 in “Anais Brasileiros De Dermatologia” Both androgenetic alopecia and alopecia areata negatively impact quality of life, with no significant difference between them.
23 citations,
January 2003 in “Journal of Pediatric Endocrinology and Metabolism” About 15% of US Army personnel use hair products containing hormone or placenta, with higher usage among non-whites, females, and enlisted personnel.
23 citations,
July 1993 in “Pharmacotherapy” Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
21 citations,
May 2016 in “The Cochrane library” Topical minoxidil helps treat female pattern hair loss, but more research needed for other treatments.
20 citations,
January 2012 in “International Journal of Trichology” Most cases of excessive hair growth in women are caused by polycystic ovarian syndrome and are linked to higher free testosterone levels.
19 citations,
January 2016 in “Annals of Dermatology” Dutasteride is safe and effective for treating hair loss, but may decrease libido.
19 citations,
January 2001 in “Dermatology + psychosomatics” The review concluded that male pattern baldness is mostly seen negatively, affecting attractiveness and social appeal.
18 citations,
May 2016 in “Aesthetic Surgery Journal” Body hair transplantation is an effective method for restoring hair in people with severe baldness and limited scalp donor hair.
18 citations,
December 2010 in “Journal of Trace Elements in Medicine and Biology” Women with AGA have more androstenedione and dihydrotestosterone, less copper and zinc; copper imbalance affects AGA; treatment improves hormones and minerals.
18 citations,
June 2010 in “Current medicinal chemistry” Treating hirsutism in women often requires a mix of medications and cosmetic methods for best results.