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Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

GPR39 is linked to certain cells in the sebaceous gland and helps with skin healing.

Finasteride reduces inflammation and improves immune response after trauma by altering hormone levels.

A new mutation in the XEDAR gene might cause a rare skin condition called hypohidrotic ectodermal dysplasia.

Spironolactone can reduce hair growth and testosterone in hirsutism, but is less effective than combined treatments.

Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.

Polygonum multiflorum extract helps hair grow longer and fights the effects of hormones that cause hair loss.

5α-Reductase inhibitors can negatively affect male sexual function and, in some cases, significantly reduce sperm count, but these effects may be reversible.

Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.

Hair restoration has evolved from surgery to drugs to potential gene therapy, with improved results and ongoing research driven by high demand.

Antiandrogen therapy helps treat genetic hair loss.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

Hair loss drugs may cause sexual issues and infertility in men.

Minoxidil works faster and is more cost-effective for treating hair loss, but platelet-rich plasma microneedling can be an alternative for those who can't use minoxidil.

The oral contraceptive ethinylestradiol/chlormadinone acetate is effective in reducing acne and improving other skin conditions related to high androgen levels.

Testosterone therapy can modestly improve sexual function in menopausal women but should be used cautiously and is not recommended for routine measurement in sexual dysfunction or hirsutism.

Ketoconazole may help regrow hair and increase follicle size, but more research needed.

A substance called compound-1 could help increase hair growth by maintaining prostaglandin levels in hair follicles.

Acne and increased body hair in teenage girls are normal but severe cases may need hormone evaluation and treatment can prevent diabetes linked to PCO.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Finasteride affects SRD5A2 gene pattern, possibly causing lasting side effects.

Finasteride can cause sexual dysfunction and depression, which may persist and require hormonal treatment.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

Topical spironolactone cream doesn't cause hormone-related side effects in the body.

LLLT is a safe, promising hair loss treatment, but more research needed.

Topical therapies show promise for hair loss and acne treatment with minimal side effects.

Finasteride-loaded ethosomes improve hair loss treatment by targeting pilosebaceous unit.

Some breast cancer patients on hormone therapy experience hair loss, and treatments like certain topical inhibitors and supplements may help without harming their cancer prognosis.

Cooling the scalp may prevent hair loss from chemotherapy, hair often grows back after treatment, and nail issues usually improve after stopping the drug.

Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.