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The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Certain genetic variants in the androgen receptor are linked to higher PSA levels, potentially affecting prostate cancer screening outcomes.

Understanding hormones is key to treating certain skin conditions.

The most common skin issues in females with Polycystic Ovary Syndrome (PCOS) are excessive hair growth, hair loss, oily skin, acne, dark skin patches, and skin tags, which may be linked to hormone and insulin levels.

Prostate cells have proteins that bind to specific hormones, which can increase protein production when activated by these hormones.

Hair problems are common and distressing for women, but increasing knowledge of treatments offers hope.

Having enough iron improves the effectiveness of a specific hair loss treatment in women.

Beard hair follicles have more androgen receptors than non-balding scalp hair follicles.

Hair growth is influenced by hormones and goes through different phases; androgens can both promote and inhibit hair growth depending on the body area.

Androgens increase norepinephrine release, promoting smooth muscle growth in male sex organs, which may contribute to benign prostatic hypertrophy.

Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.

Mouse genital development depends on male or female hormones for specific features.

The unit area trichogram is a reliable method to assess hair loss and treatment response in people with androgenic alopecia by measuring hair density and thickness.

The study found that the enzyme linked to acne is present in the same areas of both acne-affected and normal skin.

The osteopontin gene is active in a specific part of rat hair follicles during a certain hair growth phase and might affect hair cycle and diseases.

Finasteride and dutasteride might lower melanoma risk.

Male androgenetic alopecia involves hair follicle miniaturization due to DHT, with potential treatments using inhibitors and blockers.

Androgenetic alopecia, or hair loss, is caused by genetic factors and hormones, with different mechanisms in men and women, and can be linked to insulin resistance and polycystic ovary syndrome.

Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.

Dutasteride is more effective than finasteride for long-term hair growth in men with androgenic alopecia.

Antiandrogens help treat hormone-related conditions in both men and women.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Male hormones control a specific gene in hamster skin, with different hormones having varying effects.

Hirsutism is excessive male-pattern hair growth in women, often treated cosmetically or with hormone therapy if contraception is also desired.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Isotretinoin shrinks sebaceous glands without affecting hair or skin color, unlike etretinate.

Clascoterone may be an effective topical treatment for hair loss.