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The study found that androgen receptors in skin cells mainly affect the focal adhesion pathway and control the caveolin-1 gene, with implications for new treatments for related diseases.

New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.

Flutamide caused damage to male rat reproductive organs and may affect fertility.

Finasteride in male rats causes liver and metabolic issues in their offspring.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.

Testosterone may slow down wound healing and increase inflammation.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

Cyproterone acetate plus ethinyl estradiol is generally more effective in treating hirsutism, but consider side effects and patient characteristics.

Spironolactone plus finasteride reduces hirsutism more effectively.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

Minoxidil can reduce functions related to androgen receptors.