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Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

The unit area trichogram is a reliable method to assess hair loss and treatment response in people with androgenic alopecia by measuring hair density and thickness.

Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.

Key enzymes control androgen levels, affecting hormone activity and potential treatments.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Cyproterone acetate effectively reduced hair growth in hirsute patients by lowering androgen levels and altering androgen metabolism.

Testosterone helps beard and axillary hair cells grow by releasing growth factors from dermal papilla cells.

Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Testosterone affects hair follicles differently across body sites, with beard hair follicles showing more activity of a specific enzyme and presence of androgen receptors compared to scalp hair.

RU58841, a nonsteroidal anti-androgen, showed potential as a topical treatment for hair loss, increasing hair density, thickness, and length without systemic side effects in Stumptailed Macaques.

The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.

Hair loss gene linked to prostate issues.

CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.

Testosterone increases hair follicle cell growth when beard or axillary skin cells are present together.

Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.

Mouse genital development depends on male or female hormones for specific features.

Androgens increase norepinephrine release, promoting smooth muscle growth in male sex organs, which may contribute to benign prostatic hypertrophy.

The osteopontin gene is active in a specific part of rat hair follicles during a certain hair growth phase and might affect hair cycle and diseases.

Clascoterone may be an effective topical treatment for hair loss.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Human hair growth is influenced by androgen hormones, and red deer mane follicles have similar hormone receptors.

Androgens, male hormones, play a role in both men and women's health, and testosterone therapy can help women with low levels, but it's not suitable for pregnant or lactating women, or those with certain conditions.

Ganoderma lucidum may help treat prostate cancer by blocking male hormones and slowing cancer cell growth.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

New compounds were made that are promising for prostate cancer therapy.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

Dihydrotestosterone (DHT) increases oil production in skin cells by activating mTOR, and mTOR inhibitors can reduce this effect.

Female pattern alopecia is common, starts in late 20s, and is not androgen dependent.