Search

everythinglearnresearchcommunity

for

Search:↓

The most common skin issues in females with Polycystic Ovary Syndrome (PCOS) are excessive hair growth, hair loss, oily skin, acne, dark skin patches, and skin tags, which may be linked to hormone and insulin levels.

Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

The unit area trichogram is a reliable method to assess hair loss and treatment response in people with androgenic alopecia by measuring hair density and thickness.

Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.

Key enzymes control androgen levels, affecting hormone activity and potential treatments.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Cyproterone acetate effectively reduced hair growth in hirsute patients by lowering androgen levels and altering androgen metabolism.

Testosterone helps beard and axillary hair cells grow by releasing growth factors from dermal papilla cells.

Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Testosterone affects hair follicles differently across body sites, with beard hair follicles showing more activity of a specific enzyme and presence of androgen receptors compared to scalp hair.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

RU58841, a nonsteroidal anti-androgen, showed potential as a topical treatment for hair loss, increasing hair density, thickness, and length without systemic side effects in Stumptailed Macaques.

The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.

Hair loss gene linked to prostate issues.

CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.

Testosterone increases hair follicle cell growth when beard or axillary skin cells are present together.

Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.

Certain genes and X chromosome patterns may significantly contribute to the development of hair loss.

Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Mouse genital development depends on male or female hormones for specific features.

Androgens increase norepinephrine release, promoting smooth muscle growth in male sex organs, which may contribute to benign prostatic hypertrophy.

The osteopontin gene is active in a specific part of rat hair follicles during a certain hair growth phase and might affect hair cycle and diseases.

Clascoterone may be an effective topical treatment for hair loss.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Cuscuta reflexa extract may help treat hair loss caused by hormones.