research Glucocorticoid and Sex Hormone Receptors: Clinical Implications and Therapeutic Relevance
Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.
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research Circulating and Intraprostatic Sex Steroid Hormonal Profiles in Relation to Male Pattern Baldness and Chest Hair Density Among Men Diagnosed with Localized Prostate Cancers
Baldness in men with prostate cancer is linked to higher levels of certain sex hormones, but chest hair density is not.
research Combined Oral Contraceptives Promote Androgen Receptor And Estrogen Receptor Alpha Upregulation In The Female Prostate (Skene’s Paraurethral Glands) Of Adult Gerbils (Meriones Unguiculatus)
Birth control pills increase certain receptor activities in female gerbil prostate glands and can lead to prostate changes.
research Hirsutism: Diagnosis and Treatment
The document concludes that hirsutism can be managed with various treatments tailored to the individual, potentially improving quality of life.
research A Perspective on the Evolving Landscape in Male Reproductive Medicine
Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.
research New Insights Into Testosterone Biosynthesis: Novel Observations From HSD17B3 Deficient Mice
Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.
research Trends in the Development of New Drugs for the Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.
research Hormones and the Pilosebaceous Unit
Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.
research Sexual Dysfunction, Including Hypoactive Sexual Desire Disorder: Diagnosis and Treatment Recommendations
Testosterone therapy can improve sexual function in women but long-term safety is unclear.
research Regulatory Roles of Androgens in Cutaneous Wound Healing
Testosterone may slow down wound healing and increase inflammation.
research Potential Adverse Effects of Long-Term Testosterone Therapy
Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.
research Exclusive Androgenic Effect of Dehydroepiandrosterone in Sebaceous Glands of Rat Skin
DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.
research The Antiandrogenic Action of 4-Androsten-3-One-17β-Carboxylic Acid and Its Methyl Ester on Hamster Flank Organ
The chemicals 17βC and its methyl ester can block the effects of testosterone on hamster skin but not the effects of DHT.
research Topical Antiandrogens
Topical antiandrogens might treat skin issues like hair growth, balding, and acne, but finding effective treatments without side effects is challenging.
research The SAHA Syndrome: Overview and Classification
SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.
research Recent Advances in the Chemistry and Pharmacological Activity of New Steroidal Antiandrogens and 5α-Reductase Inhibitors
New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.
research Urinary Steroids in Men with Male-Pattern Alopecia
Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.
research Review of Hair Follicle Dermal Papilla Cells as In Vitro Screening Model for Hair Growth
Dermal Papilla cells are a promising tool for evaluating hair growth treatments.
research 5α-Reductase Activity in the Prostate
Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.
research Are Sex Hormones Promising Candidates to Explain Sex Disparities in the COVID-19 Pandemic?
Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.
research Novel Inhibitors of 5α-Reductase
New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
research Male Sex Hormones in Andrology Today
Testosterone is key for male sexual function, and treating hormone imbalances can improve sexual issues.
research Exposure of Xenopus Laevis Tadpoles to Finasteride, an Inhibitor of 5-Alpha Reductase Activity, Impairs Spermatogenesis and Alters Hypophyseal Feedback Mechanisms
Finasteride exposure harms tadpole reproduction and hormone balance.
research Clinical Use of 5α-Reductase Inhibitors
Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.
research Evaluating Hair Growth Promoting Effects of Candidate Substances: A Review of Research Methods
The document concludes that while lab results for hair growth promotion are promising, human trials are needed and better testing methods should be developed.
research Steroidal 5α-Reductase and 17α-Hydroxylase/17,20-Lyase (CYP17) Inhibitors Useful in the Treatment of Prostatic Diseases
Certain drugs that block specific enzymes can help treat prostate diseases.
research Evaluation of New Pregnane Derivatives as 5α-Reductase Inhibitors
New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.
research Intracrinology and the Skin
DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.
research Functional Complexity of Hair Follicle Stem Cell Niche and Therapeutic Targeting of Niche Dysfunction for Hair Regeneration
Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.
research Finasteride
Finasteride effectively treats baldness but may cause sexual side effects.