October 2023 in “Frontiers in endocrinology” Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.
April 2019 in “Journal of Investigative Dermatology” Testosterone affects androgen receptors and lipid storage in cells, while DHEA does not convert to testosterone or affect these receptors in the same way.
416 citations,
September 1997 in “Journal of Investigative Dermatology” People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.
51 citations,
January 1989 in “Journal of Investigative Dermatology” Men with male-pattern baldness have more androgen receptors in their scalp's oil glands, which may contribute to hair loss.
31 citations,
April 2015 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Androgens cause oil-producing skin cells with androgen receptors to mature and produce more oil.
24 citations,
April 2014 in “Oncotarget” Minoxidil can reduce functions related to androgen receptors.
9 citations,
January 2016 in “Skin Pharmacology and Physiology” The study concluded that both estrogen and androgen receptors, which decrease with age, are linked to skin aging and may be hormonally regulated.
6 citations,
January 2013 in “Genetics and Molecular Research” Women with hair loss have more androgen receptors in certain hair follicles.
5 citations,
June 2022 in “Frontiers in Endocrinology” Research from 2011 to 2020 shows androgen receptors could be key for prognosis and treatment in certain breast cancers.
2 citations,
January 2022 in “Skin Pharmacology and Physiology” Dexamethasone increases the activity of androgen receptors in human skin cells, which may link it to certain types of hair loss.
May 2023 in “Blood cancer discovery” Finasteride reduces AML cell growth by inhibiting androgen receptors.
6 citations,
January 2010 in “Neoplasma” Certain gene patterns in breast cancer are linked to how active hormone receptors are and could affect patient survival.
April 2023 in “Journal of Investigative Dermatology” cp-asiAR may effectively treat hair loss by targeting androgen receptors.
October 2022 in “Frontiers in Bioengineering and Biotechnology” Bioengineered nanoparticles can effectively treat hair loss by targeting specific enzymes and receptors.
1 citations,
May 2020 in “Beilstein Journal of Organic Chemistry” Scientists made a sensor that can detect a specific type of RNA related to androgen receptors quickly and accurately.
April 2019 in “Molecular Informatics” Researchers developed reliable models to predict how well certain compounds bind to androgen receptors, emphasizing the importance of atomic electronegativity.
34 citations,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Human hair growth is influenced by androgen hormones, and red deer mane follicles have similar hormone receptors.
12 citations,
January 2018 in “Pharmacology & pharmacy” Pumpkin seed products may help improve prostate and bladder health by blocking certain enzymes and hormone receptors.
207 citations,
September 2002 in “The Journal of clinical investigation/The journal of clinical investigation” Blocking testosterone speeds up wound healing in males.
115 citations,
September 2012 in “Experimental Dermatology” Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.
68 citations,
December 2014 in “Cell Biochemistry and Function” Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
66 citations,
January 2000 in “Hormone Research in Paediatrics” Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.
56 citations,
September 2013 in “Journal of Biochemistry and Molecular Biology” Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.
49 citations,
September 1986 in “British Journal of Dermatology” Hidradenitis suppurativa improves with antiandrogen therapy.
39 citations,
March 2018 in “Archives of Dermatological Research” Androgens may block hair growth signals, targeting this could treat hair loss.
27 citations,
January 1984 in “Pharmacology & Therapeutics” Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
24 citations,
March 2003 in “Best Practice & Research Clinical Endocrinology & Metabolism” Androgens, male hormones, play a role in both men and women's health, and testosterone therapy can help women with low levels, but it's not suitable for pregnant or lactating women, or those with certain conditions.
23 citations,
May 1984 in “Journal of the American Geriatrics Society” Benign Prostatic Hyperplasia may be caused by changes in how the body processes male hormones.
22 citations,
October 2011 in “Bone” Androgens affect bone and fat cell development differently based on the cells' embryonic origin.
19 citations,
March 1987 in “International Journal of Dermatology” A drug called cimetidine can help treat hair loss in women by blocking androgen receptors. However, it's not the first choice and needs more research.