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The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

The document concludes that effectively managing PCOS requires a multifaceted approach.

DHT stops hair regrowth in mice, similar to human hair loss.

Short-term finasteride treatment may lower some cell death factors in prostate cancer cells.

Most women with hirsutism have it because of PCOS, and they need long-term treatment including medication and hair removal to improve their condition.

Lack of sleep in mice leads to prostatitis by reducing certain hormones and activating an inflammatory pathway, which can be temporarily fixed with normal sleep.

Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

More research is needed to understand how testosterone is maintained in adult males.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.

The document concludes that various cosmetic and drug treatments are available for hirsutism, and some new drugs show promise.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

Nanog gene boosts stem cells, helps hair growth, and may treat hair loss.

PCOS is a genetic disorder affecting women's reproductive health, with treatments focused on symptoms like insulin resistance and fertility.

The new hydrogel treatment promotes faster hair growth and better skin health for hair loss.

New treatment using engineered nanovesicles in hydrogel improves hair growth by repairing hair follicle cells in a mouse model of hair loss.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Acne is common in women, often hormone-related, negatively affects quality of life, and requires various treatments.

Hair loss in men is common, treatable, but not curable.

FP-1 is a key protein in rat hair growth, active only during the growth phase.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

Long-term estrogen therapy in postmenopausal women can improve certain health markers, hair loss is common regardless of hormone use, stopping estrogen doesn't increase breast cancer risk, smoking does, and a balanced BMI is linked to lower mortality.

Dutasteride may help reduce brain plaque linked to Alzheimer's by affecting cell energy structures and waste removal.

Exosomes from dermal papilla cells can help grow hair and might treat hair loss.

Testosterone may help increase sexual events for women with low libido due to antidepressants.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.