Scalp cooling is recommended to prevent chemotherapy-induced hair loss, but no effective drugs are available.
141 citations,
September 2016 in “European Journal of Dermatology” Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.
97 citations,
March 2002 in “Molecular and cellular biology” Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
19 citations,
September 2019 in “EMBO molecular medicine” Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.
3 citations,
July 2017 in “Elsevier eBooks” Skin reactions are a common reason for emergency visits due to drug allergies, with some severe cases needing intensive care.
April 2024 in “Histochemistry and cell biology” N-acetylcysteine may prevent hair loss caused by chemotherapy.
146 citations,
January 2004 in “Hormones” Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
17 citations,
June 2020 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Scalp cooling is an effective way to prevent hair loss from chemotherapy.
3 citations,
October 2007 in “Expert Review of Dermatology” Hair ages due to various factors and treatments like minoxidil and finasteride can help, but more research and better public awareness are needed.
52 citations,
April 2004 in “Journal of The American Academy of Dermatology” Male pattern baldness involves three mechanisms and finasteride can help reverse it.
7 citations,
May 2014 in “Clinical practice” Cooling the scalp may prevent hair loss from chemotherapy, hair often grows back after treatment, and nail issues usually improve after stopping the drug.
54 citations,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Disruptions in hair follicle fibroblast dynamics can cause hair growth problems.
48 citations,
February 2017 in “Journal of Cosmetic Dermatology” The conclusion is to use scalp cooling, gentle hair care, and treatments like minoxidil for managing hair loss from chemotherapy, and stresses the need for more research and collaboration in this area.
44 citations,
November 2010 in “Current Opinion in Supportive and Palliative Care” Many patients find hair loss from chemotherapy very distressing, and while treatments like minoxidil and scalp cooling may help, there is no sure way to prevent it.
2 citations,
August 2020 in “Scientific reports” Genes related to keratin, skin cell differentiation, and immune functions are key in hedgehog skin and spine development.
1 citations,
September 2013 in “Elsevier eBooks” Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.
September 2014 in “Springer eBooks” Aging causes hair to gray and thin, with the timing of graying varying by race, and factors like oxidative stress and genetics can lead to hair loss.
April 2012 in “Informa Healthcare eBooks” Alopecia areata is a common autoimmune condition causing varying hair loss, diagnosed by specific patterns of inflammation around hair follicles, with several treatment options available.
418 citations,
September 2012 in “Nature” African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.
222 citations,
January 2014 in “International journal of reproductive medicine” Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.
153 citations,
October 2007 in “Cell Stem Cell” New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
133 citations,
September 2013 in “Nature Reviews Molecular Cell Biology” Different types of stem cells and their environments are key to skin repair and maintenance.
126 citations,
January 2009 in “International Journal of Trichology” Oxidative stress contributes to hair graying and loss as we age.
120 citations,
February 2009 in “Apoptosis” Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
94 citations,
February 1994 in “The journal of investigative dermatology/Journal of investigative dermatology” EGF makes hair follicles grow longer but stops hair production.
85 citations,
July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
68 citations,
March 1965 in “The BMJ” Hormones and genetics affect hair growth and patterns, with some changes reversible and others not.
67 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Chronic Telogen Effluvium may resolve after years and is diagnosed by examining the patient's history and clinical signs, with treatment aimed at underlying causes and possibly minoxidil.
66 citations,
July 2015 in “Journal of Molecular Biology” The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.
59 citations,
August 1998 in “International Journal of Dermatology” Genetics and hormones cause hair loss; finasteride treats it safely.