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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Oestrogens are key for bone growth during puberty in both boys and girls.

HairMax LaserComb® effectively promotes hair growth and stops hair loss in males with androgenetic alopecia, with no serious side effects.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Guidelines for diagnosing common hair loss include detailed history, clinical examination, and various diagnostic techniques.

Laser device increases hair density, safe for treating hair loss in men and women.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

Minoxidil helped bald patient regrow hair.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.