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      Is Dehydroepiandrosterone a Hormone?

      research Is dehydroepiandrosterone a hormone?

      403 citations , November 2005 in “Journal of Endocrinology”
      This review discusses the role of DHEA in intracrinology, highlighting its impact on breast and prostate cancer treatment and potential as a menopause therapy, but reports no new research findings.
      Complications of Cushing's Syndrome: State of the Art

      research Complications of Cushing's syndrome: state of the art

      374 citations , May 2016 in “˜The œLancet. Diabetes & endocrinology”
      This article reviews the clinical complications and increased mortality risks associated with Cushing's syndrome but does not present new clinical data; it emphasizes the need for prompt treatment to mitigate these risks.
      Sexual Hormones in Human Skin

      research Sexual Hormones in Human Skin

      305 citations , February 2007 in “Hormone and metabolic research”
      This review discusses the roles of androgens and estrogens in skin functions and disorders, and highlights the use of estrogen-progestin treatments and anti-androgens in managing hirsutism and acne, without reporting new results.
      Hirsutism

      research Hirsutism

      271 citations , December 2005 in “New England journal of medicine/˜The œNew England journal of medicine”
      This article discusses evaluation and treatment options for a 19-year-old woman with slowly progressive hair growth and reports no new clinical findings.
      Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis

      research Transforming growth factor-β in stem cells and tissue homeostasis

      245 citations , January 2018 in “Bone Research”
      This review discusses the role of TGF-β signaling in stem cell recruitment and tissue regeneration, indicating that abnormalities in TGF-β activation contribute to various major diseases and suggesting avenues for therapeutic intervention.
      Eph Receptors and Ephrins: Therapeutic Opportunities

      research Eph Receptors and Ephrins: Therapeutic Opportunities

      222 citations , October 2014 in “Annual Review of Pharmacology and Toxicology”
      This review discusses the roles of Eph receptors and ephrins in various diseases, highlighting their potential as therapeutic targets, but it presents no new research findings.
      The Diagnosis of Polycystic Ovary Syndrome in Adolescents

      research The diagnosis of polycystic ovary syndrome in adolescents

      212 citations , May 2010 in “American Journal of Obstetrics and Gynecology”
      This article suggests using only firm criteria to diagnose polycystic ovary syndrome in adolescents, due to the evolving nature of its features during this period.
      Gender-Linked Differences in Human Skin

      research Gender-linked differences in human skin

      205 citations , July 2009 in “Journal of Dermatological Science”
      This review discusses gender-linked skin differences, such as hormone metabolism and sebum production, and reports no new findings; it suggests these insights might inform male-specific dermatological treatments or cosmetic products.
      Evaluation and Treatment of Male and Female Pattern Hair Loss

      research Evaluation and treatment of male and female pattern hair loss

      203 citations , December 2004 in “Journal of The American Academy of Dermatology”
      This article reviews the historical developments in understanding and treating male pattern hair loss, emphasizing the role of dihydrotestosterone and 5α-reductase inhibitors, but reports no new clinical findings.
      The Evaluation and Management of Hirsutism

      research The evaluation and management of hirsutism*1

      195 citations , May 2003 in “Obstetrics and gynecology (New York. 1953. Online)/Obstetrics and gynecology”
      This review discusses the diagnosis and treatment of hirsutism, emphasizing that a systematic evaluation can determine its cause, while combination therapy effectively manages the condition for most patients.
      The Effects of Estrogens on Linear Bone Growth

      research The effects of oestrogens on linear bone growth

      173 citations , May 2001 in “Human reproduction update”
      This review discusses the role of oestrogens in stimulating growth hormone secretion and influencing linear bone growth in children, and reports no new clinical results; the authors suggest that oestrogens play a key role in pubertal growth spurts for both genders.
      Androgens and Human Hair Growth

      research Androgens and human hair growth

      157 citations , April 1994 in “Clinical endocrinology”
      Androgens can cause hair growth in some areas and hair loss on the scalp.
      Androgenetic Alopecia: A Review

      research Androgenetic alopecia: a review

      153 citations , March 2017 in “Endocrine”
      This review examines recent advances in understanding the pathophysiology and molecular mechanisms of androgenetic alopecia, highlighting two major genetic risk loci, but does not report new clinical findings.
      Hormone Therapy for Transgender Patients

      research Hormone therapy for transgender patients

      146 citations , December 2016 in “Translational Andrology and Urology”
      This review discusses the creation of transgender-specific guidelines by WPATH and the Endocrine Society, based mostly on clinical experience, and reports no new results.
      The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside

      research The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside

      144 citations , November 2020 in “Frontiers in immunology”
      This study summarizes how the IL-23/IL-17 axis contributes to inflammatory skin diseases like psoriasis and highlights that biologics targeting this pathway, including monoclonal antibodies against IL-23 and IL-17, have shown efficacy in clinical trials for these conditions.
      Molecular Mechanisms of Viral Oncogenesis in Humans

      research Molecular mechanisms of viral oncogenesis in humans

      141 citations , August 2018 in “Nature Reviews Microbiology”
      This review discusses the molecular mechanisms by which oncogenic viruses contribute to cancer development through manipulation of host cellular functions and highlights the need for further research into virus-associated cancers, reporting no new results.
      A New Look at the 5-Alpha-Reductase Inhibitor Finasteride

      research A New Look at the 5?-Reductase Inhibitor Finasteride

      137 citations , March 2006 in “Cns Drug Reviews”
      This review explores finasteride's effects on neuroactive steroid levels and their potential influence on disorders like depression and alcohol withdrawal but reports no new clinical findings.
      Estrogens and the Skin

      research Estrogens and the skin

      137 citations , June 2005 in “Climacteric”
      This review indicates that estrogen loss during menopause significantly impacts skin health, while estrogen treatment may increase skin collagen, thickness, and elasticity, though effects on other skin characteristics are inconsistent.
      The Role of Vitamins and Minerals in Hair Loss: A Review

      research The Role of Vitamins and Minerals in Hair Loss: A Review

      134 citations , December 2018 in “Dermatology and Therapy”
      This review discusses the potential role of vitamins and minerals in managing non-scarring alopecia but reports no clinical results; the authors advocate for further controlled trials to explore these relationships.
      Regulatory T Cells: The Many Faces of Foxp3

      research Regulatory T Cells: the Many Faces of Foxp3

      125 citations , September 2019 in “Journal of Clinical Immunology”
      This review summarizes recent advances in Treg cell biology, focusing on Foxp3's role in immune regulation and therapeutic reprogramming for immune dysregulatory disorders, but reports no new clinical results.