1 citations
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December 2024 in “Journal of Orthopaedic Research®” In this study, researchers developed a novel method combining in silico and in vitro techniques to discover Aromoline, a potential osteoarthritis treatment that increases type II collagen expression in chondrocytes by targeting the dopamine receptor D4.
246 citations
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April 1976 in “Annals of Surgery” In this study, a syndrome of zinc deficiency was observed in adults receiving intravenous feeding, with zinc supplementation improving symptoms except for delayed hair regrowth.
36 citations
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January 2014 in “Evidence-based Complementary and Alternative Medicine” This study found that men with androgenetic alopecia treated with pumpkin seed oil for 24 weeks experienced a notable 40% increase in hair count compared to a 10% increase with a placebo.
6 citations
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September 2018 in “International Journal of Molecular Sciences” This study found that intramuscular injections of a PRP-derivative in healthy beagle dogs did not result in statistically significant changes in lumbar muscle tissue or IGF-1 blood concentration, suggesting the treatment may be safe at therapeutic doses.
4 citations
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November 2024 in “International Journal of Dermatology” This study examines the link between testosterone use and hair health in males, stressing the importance of developing guidelines for safe usage due to associated health risks like liver toxicity, gynecomastia, and hair loss.
March 2024 in “Post-Graduate Medical Journal of NAMS” In this study, researchers found that 20% of patients with androgenetic alopecia also had metabolic syndrome, suggesting a notable prevalence similar to other studies conducted in similar settings.
The document concludes that scientists created various steroids with different properties, including a more effective semi-synthetic vitamin D.
35 citations
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October 2011 in “Medicine and science in sports and exercise” This review discusses the role of skeletal muscle in synthesizing bioactive androgens, highlighting that intramuscular androgens may influence muscle via intracrine action, but their precise function remains unclear.
115 citations
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March 2001 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” This article reviews how different 5alpha-reductase and 3alpha-HSD enzymes impact androgen levels and highlights their potential as drug targets for androgen-related diseases, but provides no new experimental findings.
46 citations
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September 2014 in “Steroids” This review suggests that brassinosteroids may have similar biological activities in both plants and other organisms, prompting further exploration of steroid regulation mechanisms across different life forms.
41 citations
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March 2007 in “Steroids” This article reviews recent advances in the synthesis of oxasteroids and reports no new experimental results.
28 citations
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November 2004 in “Endocrinology” This study by Gao et al. reports that two nonsteroidal selective androgen receptor modulators, S1 and S4, demonstrated tissue-selective actions in rats, suppressing prostate growth while maintaining muscle growth without altering hormone levels.
5 citations
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April 2021 in “Journal of Mind and Medical Sciences” This review examines the interconnected roles of bone, adipose tissue, and the central nervous system in regulating energy balance, providing no new experimental results.
1 citations
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December 2006 in “Burns” New therapies for burn wounds show promise in reducing pain, infection risk, and improving healing and physical outcomes.
3 citations
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January 2016 in “Elsevier eBooks” This article discusses the various roles of steroids in vertebrate organ systems and notes several glucocorticoids that were among the Top 200 Drugs by sales in the 2010s, but it reports no new clinical findings.
July 2012 in “The Journal of Urology” This abstract reviews testosterone supplementation with and without a dual 5α-reductase inhibitor on fat-free mass in men with suppressed testosterone production and reports no new research findings.
1 citations
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October 2022 This study assessed the potential for Ocean Thermal Energy Conversion power in Fiji, finding higher power output and efficiency during summer due to greater temperature differences between surface and deep sea waters.
January 2024 in “Wiadomości Lekarskie” This study found that engaging in outdoor physical activities significantly reduced the odds of increased HbA1C levels, lower HDL-cholesterol, and obesity among patients with metabolic syndrome, suggesting potential health benefits for this population.
7 citations
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January 2018 in “Australian Prescriber” This review discusses the presence of undeclared substances, including androgenic steroids, in sports supplements and emphasizes potential health risks, without providing new results; it advises caution and consultation on supplement use.
1 citations
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February 1988 in “The BMJ” The document explains different hair and scalp conditions, including common hair loss after pregnancy or illness, drug-induced hair loss, hereditary excessive hair growth, patterned baldness, autoimmune hair loss, and permanent loss due to skin disease, with generally limited treatment options.
October 2020 in “System Dynamics Review” This study models the pathways of nandrolone and its metabolites in the body and suggests methods to counteract finasteride's role in enabling PED users to cheat drug tests.
This book overview summarizes advances in integrative dermatology without presenting any new research findings.
June 2026 in “International Journal on Science and Technology” This source redefines anti-aging medicine as "precision healthspan pharmacology," suggesting that rather than just treating diseases or accepting aging, pharmacology should focus on expanding functional capacity across various health domains, while emphasizing the importance of fundamental physiological and psychosocial health factors.
37 citations
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June 2011 in “Journal of Cellular Biochemistry” In this study, transgenic male mice over-expressing the androgen receptor in mesenchymal stem cells showed reduced fat mass and improved glucose clearance, suggesting enhanced androgen sensitivity may alter body composition.
20 citations
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January 2003 in “Chemical and Pharmaceutical Bulletin” This study reports that five new progesterone derivatives demonstrated inhibitory activity against the 5α-reductase enzyme and binding affinity for the androgen receptor in an in vitro hamster model.
15 citations
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January 1998 in “Journal of Clinical Periodontology” Finasteride helps treat hair loss by blocking enzyme activity.
9 citations
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August 2000 in “Journal of Periodontal Research” Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.
5 citations
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January 2017 in “Endocrinology” This chapter reviews the biosynthesis, mechanism of action, and therapeutic effects of testosterone and related androgens, but reports no new research findings.
5 citations
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August 2012 in “Journal of Dermatology” This report presents a case where female pattern hair loss might be linked to tamoxifen use, with increased androgen receptor expression observed in the affected scalp area.
2 citations
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November 2017 in “Elsevier eBooks” This article discusses the role of the androgen receptor in regulating development and homeostasis, and reviews treatment approaches for conditions related to hormone imbalances, without reporting new clinical findings.