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Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.

The research suggests that the ZP4 gene is linked to egg development in women with PCOS but requires more study to understand its role in infertility.

The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

Ketoconazole increases finasteride's effectiveness and lifespan in the body.

Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.

A gene in Sebekia benihana, CYP-sb21, is needed for a specific reaction on the drug Cyclosporine A, which could be important for hair growth without affecting the immune system.

Quinoline alkaloids from Cinchona may help treat cancer, diabetes, fungal infections, and promote hair growth.

Marine microbes could be used in cosmetics for sun protection, skin care, and possibly preventing hair loss.

Harlequin mutant mice have hair loss due to low AIF protein levels and retroviral element activity.

Chromium salts may help with insulin sensitivity in PCOS, but more research is needed to confirm their overall effectiveness and safety.

Cellulose nanocrystals are promising for making effective, sustainable sensors for various uses.

The unique coat of lykoi cats is likely caused by new variants in the Hairless gene.

Hairless mammals have genetic changes in both their protein-coding and regulatory sequences related to hair.

The SYP123-VAMP727 complex is important for transporting materials that harden the root hair shank in Arabidopsis.

The Asiatic lion has very low genetic diversity and unique genetic traits, highlighting the need for its conservation.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

Climate-related nutritional stress may cause hair loss in juvenile male Guadalupe fur seals.

NAC1 controls certain enzymes that reduce root hair growth in Arabidopsis.

Keratin gene expression helps understand different types of skin cells and their development, and should be used carefully as biological markers.

A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.

C-scores can help predict gain-of-function and loss-of-function mutations.

Herbal ingredients like aloe vera and hibiscus can help with hair problems like hair loss and dandruff.

Annurca apple extract may help treat hair loss and protect against oxidative stress.

Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.