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Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Obesity changes androgen levels in women with PCOS, leading to higher testosterone relative to androstenedione.

Gender-affirming hormone therapy affects metabolism differently based on treatment type.

Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.

Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.

Nutritional supplements may help improve hair growth in female pattern hair loss.

The study found key factors in the cause of hidradenitis suppurativa, its link to other diseases, and identified existing drugs that could potentially treat it.

Women with PCOS should be screened for heart disease risk and manage their health to prevent it.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Women with PCOS have lower ghrelin levels and a weaker response to sugar, which might affect their feeling of fullness and lead to overeating.

Certain microRNAs in the fluid around eggs are linked to Polycystic Ovary Syndrome and may help diagnose it.

People with polycystic ovary syndrome may have a higher risk of heart problems due to abnormal nervous system control of their heart and blood pressure.

More PDCD4 is linked to obesity, insulin problems, and cell death in ovaries for those with polycystic ovary syndrome.

Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.

A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.

Researchers created a skin graft that senses blood glucose and could treat diabetes using CRISPR-edited stem cells.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

Finasteride doesn't affect omeprazole metabolism in Japanese people.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

Type 2 diabetes in youth is increasing, with high treatment failure rates and more severe than Type 1; certain drugs can lower lipid levels effectively with varying side effects, and apples may benefit heart health like statins but with fewer side effects.

Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

OM-X® helped prevent negative effects of Vitamin C deficiency in mice, suggesting it could protect organs and regulate metabolism.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Myo-inositol and D-chiro-inositol improve hormonal and physical symptoms in teenage girls with PCOS.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Aquaporins could be new drug targets for treating polycystic ovary syndrome.