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      Hair's Zinc Level in Androgenic Alopecia

      research Hair's Zinc Level in Androgenic Alopecia

      January 2016 in “American Journal of Clinical and Experimental Medicine”
      Lower zinc levels in hair are linked to more severe male pattern baldness, but blood zinc levels don't show this link. Age also increases baldness severity.
      Androgenetic Alopecia

      research Androgenetic Alopecia

      February 2008 in “CRC Press eBooks”
      Androgenetic alopecia is a genetic hair loss condition, more severe in men, and can also be caused by hormonal imbalances in women.
      Analysis of Steroids and Binding Proteins in the Blood of Women with Androgenetic Alopecia

      research Analysis of Steroids and Binding Proteins in the Blood of Women with Androgenetic Alopecia

      July 1994 in “PubMed”
      Women with androgenetic alopecia have normal levels of most blood steroids and binding proteins, but higher dehydroepiandrosterone. Some also have low "sex hormone-binding globulin" and "corticosteroide-binding globulin" capacity, and high "free androgen index" and "free cortisol index". Diane treatment can normalize these levels and improve hair conditions.
      Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin

      research Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin

      18 citations, October 2021 in “Frontiers in Physiology”
      Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
      Clinical Case Notes: Lipoid Proteinosis - A Rare Disorder with Pathognomonic Lid Lesions

      research Clinical Case Notes: Lipoid Proteinosis - A Rare Disorder with Pathognomonic Lid Lesions

      13 citations, February 2004 in “Clinical and Experimental Ophthalmology”
      A baby boy with 13q deletion syndrome had eye cancer, a woman's vision improved after stopping a breast cancer drug, a man developed cataracts from using Propecia, and a rare skin disorder called Lipoid Proteinosis was discussed. Also, a tool called OCT is useful for diagnosing macular diseases.
      The Clinical Applications of Five-Alpha Reductase Inhibitors

      research The Clinical Applications of Five-Alpha Reductase Inhibitors

      2 citations, April 2021 in “Canadian Journal of Urology”
      Five-alpha reductase inhibitors, like finasteride and dutasteride, can treat enlarged prostates, improve urination, reduce need for prostate surgery, and lower the risk of prostate cancer, but may increase the risk of higher grade prostate cancer. They can also treat male pattern baldness.
      Androgenetic Alopecia: A Review and Emerging Treatments

      research Androgenetic Alopecia: A Review and Emerging Treatments

      1 citations, July 2017 in “Clinical research in dermatology”
      Hair loss, known as Androgenetic Alopecia, is often caused by hormones and can be diagnosed using noninvasive techniques. Treatments include topical minoxidil and oral finasteride, with new treatments being explored. There may also be a link between this type of hair loss and heart disease risk.
      Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways

      research Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways

      1 citations, May 2017 in “InTech eBooks”
      Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
      Antiandrogens and Androgen Inhibitors in Dermatologic Treatments

      research Antiandrogens and Androgen Inhibitors in Dermatologic Treatments

      November 2020 in “Elsevier eBooks”
      Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.
      Proceedings of the Ninth World Congress for Hair Research 2015

      research Proceedings of the Ninth World Congress for Hair Research 2015

      January 2017 in “Journal of Investigative Dermatology Symposium Proceedings”
      The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
      Dermatological History and Examination

      research Dermatological History and Examination

      December 2004 in “Medicine”
      A thorough history and examination are crucial for diagnosing skin diseases, which affect up to a third of people. This includes details about skin lesions, medication, general health, lifestyle, family, and contacts, as well as examining the rash, hair, nails, and mucous membranes. Changes in hair and nails can also indicate other medical and skin disorders.
      Hair Restoration and Removal

      research Hair Restoration and Removal

      May 2004 in “Facial Plastic Surgery Clinics of North America”
      Hair restoration techniques improved rapidly in 2004, leading to more natural results, with a shift to microscopic methods and diverse treatments including medical management, cloning, and surgical techniques. Laser hair removal was also mentioned.
      Hair Restoration and Removal

      research Hair Restoration and Removal

      May 2004 in “Facial Plastic Surgery Clinics of North America”
      Hair restoration techniques improved rapidly in 2004, leading to more natural results, with a shift to microscopic methods and diverse treatments including medical management, cloning, and surgical techniques. Laser hair removal was also mentioned.
      Dermatological Drugs and Topical Agents

      research Dermatological Drugs and Topical Agents

      January 2004 in “Side effects of drugs annual”
      Certain skin drugs and topical agents, including some natural extracts and fragrances, can cause allergic reactions. Some hair dyes and extensions, as well as minoxidil, a hair growth treatment, can also cause allergies. Botulinum toxin A can effectively reduce sweat but may have temporary side effects.
      Corrective Hair Restoration Techniques for Aesthetic Problems of Temporoparietal Flaps

      research Corrective Hair Restoration Techniques for Aesthetic Problems of Temporoparietal Flaps

      March 2003 in “Dermatologic Surgery”
      Dr. Dominic A. Brandy shared methods to fix aesthetic problems from old hair restoration techniques, using methods like follicular unit grafting and scalp removal, which helped patients look more natural after surgery. He also suggested using oral finasteride and topical minoxidil to control hair loss in most men with baldness, especially those who had flap surgery.
      Hair Regrowth Boosting Via Minoxidil Cubosomes: Formulation Development, In Vivo Hair Regrowth Evaluation, Histopathological Examination, and Confocal Laser Microscopy Imaging

      research Hair Regrowth Boosting Via Minoxidil Cubosomes: Formulation Development, In Vivo Hair Regrowth Evaluation, Histopathological Examination, and Confocal Laser Microscopy Imaging

      February 2023 in “International Journal of Pharmaceutics”
      A new version of minoxidil, a hair loss treatment, was made using nanotechnology. This version, called minoxidil cubosomes, works better and causes fewer skin reactions than the old version. It also penetrates and stays in the skin better, promoting hair regrowth. It's safe and could be a good alternative to current treatments.
      Androgenic Alopecia in Female

      research Androgenic Alopecia in Female

      November 2023 in “El-Minia Medical Bulletin”
      Sinclair grading effectively identifies female androgenic alopecia patterns, with Grade III most common.
      Alopecia Areata Update

      research Alopecia Areata Update

      391 citations, January 2010 in “Journal of The American Academy of Dermatology”
      Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.

      research Alopecia Areata Update

      244 citations, January 2010 in “Journal of the American Academy of Dermatology”
      The document says current treatments for alopecia areata do not cure or prevent it, and it's hard to judge their effectiveness due to spontaneous remission and lack of studies.