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Most legal cases about 5α-reductase inhibitors, drugs for hair loss and prostate issues, complain about side effects and delayed cancer diagnosis, with most lawsuits settled out of court.

Five-alpha reductase inhibitors, like finasteride and dutasteride, can treat enlarged prostates, improve urination, reduce need for prostate surgery, and lower the risk of prostate cancer, but may increase the risk of higher grade prostate cancer. They can also treat male pattern baldness.

Oral finasteride and dutasteride may negatively affect erectile function in rats.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

TNF-alpha inhibitors can cause various immune-related skin issues.

Taking 5-alpha reductase inhibitors does not increase breast cancer risk in men.

The document concludes that women should not use 5-alpha-reductase inhibitors due to the risk of birth defects and limited effectiveness.

5-alpha-reductase inhibitors might help slow down low-risk prostate cancer, but their use should be cautious.

The dutasteride nanoemulsion could improve hair loss treatment by enhancing drug penetration and retention in hair follicles.

5-Alpha reductase inhibitors are safe long-term but may be outdated for preventing less significant prostate cancer.

A 36-year-old person with a female appearance but male chromosomes was diagnosed with a rare enzyme deficiency affecting sexual development.

Dutasteride and finasteride can help increase hair growth gene expression but need further improvement.

Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.

Minoxidil 2% is more effective for female hair loss, but botanicals have fewer side effects.

5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.

5-alpha-reductase inhibitors help treat urinary symptoms from an enlarged prostate.

Babies were mostly born healthy from fathers who took finasteride, but some pregnancies ended early; more research is needed.

Some medications for inflammation can cause a condition with scalp rashes and hair loss, often linked to Crohn's disease, and may require treatment changes to prevent permanent hair loss.

Dutasteride is more effective than Finasteride in reducing prostate size and PSA levels, but both drugs have similar side effects.

A Saudi individual initially identified as a girl had a genetic disorder affecting gender development.

5 alpha reductase inhibitors can cause sexual, cognitive, and muscle side effects, and may slightly increase aggressive cancer risk.

Finasteride improves heart function in obese and aging male rats by reducing oxidative stress and p53 protein levels.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Using 5-alpha reductase inhibitors may lower the risk of breast cancer in females.

Long-term finasteride treatment reduces depression and brain issues in obese male rats.

Finasteride harms Daphnia magna's reproduction, growth, and metabolism.

5-alpha-reductase inhibitors lower PSA density but higher PSA density indicates disease progression.

Taking medication for hair loss might cause sexual problems.

Store Tectona grandis leaf extracts in slightly acidic, light-protected conditions for best stability.