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Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

Sleep, testosterone levels, and a specific enzyme activity affect skin oil production in women.

Finasteride safely lowers DHT levels without affecting hormone levels, helping with conditions like enlarged prostate, acne, and hair loss.

Hair loss drugs like finasteride may cause lasting sexual and mood side effects, and more research is needed to understand these risks.

Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.

5-Alpha reductase inhibitors may prevent prostate cancer but are not widely used due to concerns about trial relevance and potential risks, and more research is needed to confirm long-term benefits.

Dutasteride effectively and safely treats male hair loss for over a year.

5-Alpha-Reductase inhibitors shorten COVID-19 recovery time in men.

5-alpha reductase inhibitors might worsen lung recovery in COVID-19 patients, suggesting a pause in their use.

Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

5-alpha reductase inhibitors may reduce bladder cancer recurrence and improve survival.

Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.

Finasteride may affect PNMT, causing side effects.

Older patients sticking to their prostate medication saw lasting health benefits.

Most legal cases about 5α-reductase inhibitors, drugs for hair loss and prostate issues, complain about side effects and delayed cancer diagnosis, with most lawsuits settled out of court.

Oral finasteride and dutasteride may negatively affect erectile function in rats.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

5-alpha-reductase inhibitors might help slow down low-risk prostate cancer, but their use should be cautious.

The dutasteride nanoemulsion could improve hair loss treatment by enhancing drug penetration and retention in hair follicles.

5-Alpha reductase inhibitors are safe long-term but may be outdated for preventing less significant prostate cancer.

A 36-year-old person with a female appearance but male chromosomes was diagnosed with a rare enzyme deficiency affecting sexual development.

Dutasteride and finasteride can help increase hair growth gene expression but need further improvement.

Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.

Minoxidil 2% is more effective for female hair loss, but botanicals have fewer side effects.

5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.

5-alpha-reductase inhibitors help treat urinary symptoms from an enlarged prostate.