48 citations,
October 1996 in “Dermatologic clinics” Some treatments can help with hair regrowth in alopecia areata, but results vary and long-term use is often needed without changing the disease's outcome.
47 citations,
June 2017 in “Journal of dermatology” New treatments for alopecia areata show promise, but no cure exists and responses to treatments vary.
47 citations,
October 2014 in “Expert Opinion on Emerging Drugs” New alopecia treatments aim for better results and fewer side effects.
47 citations,
September 1995 in “British Journal of Dermatology” Diphencyprone therapy for hair loss can cause vitiligo.
47 citations,
May 1995 in “Journal of Investigative Dermatology” Hair follicles in people with alopecia have lower levels of a key blood vessel growth protein.
46 citations,
August 2019 in “Journal of the European Academy of Dermatology and Venereology” People with hair loss conditions experience more anxiety, depression, and a lower quality of life than those without these conditions.
46 citations,
October 2018 in “JCI insight” CD8+ T cells are involved in alopecia areata and may cause disease relapse.
46 citations,
July 2007 in “Journal of the American Academy of Dermatology” Alopecia areata causes significant emotional distress, including high rates of depression and anxiety.
46 citations,
May 1997 in “British journal of dermatology/British journal of dermatology, Supplement” Vitiligo is not linked to coeliac disease, but a small number of alopecia areata patients may have it, suggesting they should be tested for coeliac disease.
46 citations,
November 1995 in “The Journal of Dermatology” Alopecia areata was most common in people in their 30s and 40s, with some family history and a higher relapse rate, and larger bald areas responded better to specific immunotherapy.
46 citations,
June 1990 in “Archives of dermatology” Combining 5% minoxidil and 0.5% anthralin can help regrow hair in some severe alopecia areata patients.
45 citations,
April 2019 in “International Immunology” The study concluded that immune cells attacking hair follicles cause hair loss in alopecia, with genetics and environment also playing a role, and highlighted the potential of certain treatments.
45 citations,
May 2018 in “Stem Cell Research & Therapy” Using patients' own fat-derived cells to treat alopecia areata significantly improved hair growth and was safe.
45 citations,
January 2018 in “International Journal of Dermatology” Nail problems are common in people with alopecia areata, often leading to cosmetic and functional issues, but more research is needed for treatment guidelines.
45 citations,
December 2014 in “Journal of the European Academy of Dermatology and Venereology” Plasmacytoid dendritic cells are a key factor in causing hair loss in alopecia areata and could help differentiate it from other hair loss conditions.
45 citations,
March 2013 in “European Journal of Plastic Surgery” Injecting platelet-rich plasma is a safe and effective way to treat hair loss.
45 citations,
January 2010 in “International journal of trichology” Topical immunotherapy, especially with DPCP, is effective for treating severe alopecia areata.
45 citations,
November 2009 in “British Journal of Dermatology” Women with early hair loss have higher blood pressure and aldosterone; screening and treatment may help.
45 citations,
July 2008 in “International Journal of Dermatology” Sulfasalazine may help treat persistent alopecia areata.
44 citations,
November 2016 in “Journal of The American Academy of Dermatology” The updated SALT II tool offers a more precise way to measure scalp hair loss.
44 citations,
September 2015 in “Annals of Oncology” Targeted cancer therapies have a significant but lower risk of causing hair loss compared to chemotherapy.
44 citations,
April 2019 in “Journal of the American Academy of Dermatology” Cyclosporine showed some improvement in alopecia areata but results were not statistically significant.
44 citations,
October 2017 in “Journal of the American Academy of Dermatology” Tofacitinib is effective and safe for treating severe hair loss in Korean patients.
44 citations,
April 2017 in “International Journal of Dermatology” No treatment is completely effective for alopecia totalis and alopecia universalis.
44 citations,
February 2015 in “Journal of the American Academy of Dermatology” Combining diphenylcyclopropenone with anthralin is more effective for hair regrowth in alopecia areata than using diphenylcyclopropenone alone, but may cause more side effects.
44 citations,
August 2014 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Methotrexate is a promising and safe treatment for severe alopecia areata, with better results when combined with corticosteroids.
44 citations,
December 2010 in “Journal of Investigative Dermatology” Alopecia areata seriously lowers quality of life, especially affecting self-image, mental health, and social life.
44 citations,
October 2009 in “Journal of the American Academy of Dermatology” Topical bexarotene 1% gel might help regrow hair in alopecia areata and is generally safe.
44 citations,
December 2005 in “Journal of Investigative Dermatology” Certain genetic markers, especially the MICA gene, are linked to alopecia areata.
44 citations,
May 1980 in “Archives of Dermatology” "20-nail dystrophy" can have multiple causes.