Cutaneous Atrophy and Alopecia After Greater Occipital Nerve Injection Using Triamcinolone

October 2012 in “ Headache The Journal of Head and Face Pain ”

Giorgio Lambru, Susie Lagrata, Manjit Matharu

cutaneous atrophy alopecia greater occipital nerve blockade triamcinolone lidocaine corticosteroid Cushing's syndrome methylprednisolone betamethasone skin thinning hair loss GON blockade Kenalog Xylocaine steroid Cushing's disease Depo-Medrol Celestone

TLDR Triamcinolone injections for headaches can cause skin thinning and hair loss.

The document reported on the occurrence of cutaneous atrophy and alopecia in 4 patients following greater occipital nerve (GON) injections using triamcinolone and lidocaine for headache treatment. While GON infiltration was generally well tolerated and effective, particularly in cluster headache, corticosteroid-related side effects such as Cushing's syndrome and local cutaneous changes were noted. The study suggested that alternative steroid preparations like methylprednisolone and betamethasone might be more suitable for GON blockade to avoid these adverse effects.

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research Intralesional Betamethasone Versus Triamcinolone Acetonide in the Treatment of Localized Alopecia Areata: A Within-Patient Randomized Controlled Trial

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Triamcinolone acetonide is slightly more effective than betamethasone for hair regrowth in localized alopecia areata.