December 2025 in “Value in Health” Alopecia areata significantly strains healthcare and finances in the UAE, needing better management.
December 2020 in “Galen Medical Journal” This study observed that patients with alopecia areata and androgenic alopecia have significantly more perifollicular and perivascular mast cells compared to healthy individuals, particularly in those over 40 and with greater disease severity.
7 citations
,
November 2017 in “Cureus” This report introduces a new potential sign, paired ear creases of the helix, which may have relevance to cardiovascular disease similar to diagonal ear lobe creases, in a case of coronary artery disease.
June 2023 in “Value in Health” Alopecia areata treatments often cause headaches and infections, highlighting the need for safer options.
1 citations
,
April 2024 in “Journal of Clinical Medicine” This study found that patients with severe alopecia areata demonstrated reduced corneal sensitivity and increased corneal staining, and exhibited altered topographic and biomechanical eye parameters compared to controls, suggesting a possible increased risk of keratoconus and the necessity for regular ophthalmological exams.
23 citations
,
September 1957 in “Archives of Dermatology” This study investigated alkaline phosphatase activity in scalp biopsies from patients with alopecia areata and totalis, but provides no new conclusive clinical results.
17 citations
,
April 2017 in “International Journal of Biological Macromolecules” This study found that alginate beads containing monoolein demonstrated promising potential for managing wet wounds by better absorbing excess exudate and delivering adenosine locally, favoring drug localization in damaged porcine skin compared to an aqueous solution without affecting skin viability.
38 citations
,
September 1997 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified histologic lesions and a defect in adhesion molecules causing hair loss in mice with the bal mutation, linked to a mutation in the desmoglein 3 gene.
1 citations
,
January 2019 in “Zenodo (CERN European Organization for Nuclear Research)” This anatomical study on Eclipta alba concluded that unique secretory structures in stems and leaves may serve as identifying features of the plant and the Asteraceae family.
July 2025 in “Journal of Investigative Dermatology” Alopecia areata involves complex immune cell interactions, especially between CD8+ T cells and macrophages, which could help develop new treatments.
July 2024 in “Journal of Investigative Dermatology” This study found that in mice with alopecia areata, CD8+ T cells showed clonal expansion and specific regulatory networks, which might help identify new therapeutic targets for patients not responding to JAK inhibitors.
January 2026 in “Elsevier eBooks”
December 2023 in “The Sri Lanka Journal of Dermatology” In this case report, a 12-year-old girl was diagnosed with alopecia as part of the rare ALX4-related frontonasal dysplasia sequence, highlighting the condition's uniqueness in pediatric dermatology.
20 citations
,
December 2017 in “Journal of Investigative Dermatology Symposium Proceedings” This article presents a computer imaging algorithm that may automate and enhance the Severity of Alopecia Tool scoring for alopecia areata through texture analysis of pediatric images.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, a herbal hair cream containing natural ingredients like Jamalgota and Amla was developed and evaluated, with Batch 3 showing promising results in texture, pH balance, spreadability, and stability, suggesting it may be a safe and effective option for managing alopecia.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, a herbal hair cream formulated with natural ingredients like Jamalgota and Neem oil was evaluated for managing alopecia; Batch 3 showed the best performance in texture, stability, and spreadability, with promising results as a safe alternative for promoting healthy hair growth.
September 2020 in “Eureka: Health Sciences” In this study, the researchers developed an optimal emulgel formulation for treating androgenic alopecia, determining that a base with 0.3% Carbomer Ultraz 10, 0.1% potassium sorbate, and 0.2% triethanolamine offered the best properties for drug release, application compliance, safety, and stability.
May 2026 in “Revista fisio&terapia.” This narrative literature review found that combined therapies such as minoxidil, microneedling, and platelet-rich plasma are more effective than isolated treatments for androgenetic alopecia, improving hair density and quality. The study highlights the role of pharmaceutical intervention in enhancing treatment adherence and clinical outcomes.
2 citations
,
December 2018 This study found that dermatoscopy can quickly and non-invasively detect facial vellus hair involvement in patients with alopecia frontal fibrosante, occurring frequently and associated with specific facial lesions.
December 2024 in “Brazilian Journal of Health Review” This article reviews the general, pathophysiological, diagnostic, and therapeutic aspects of alopecia frontal fibrosante, highlighting its irreversible nature and the importance of early diagnosis, but it reports no new clinical results.
95 citations
,
January 2004 in “Archives of Dermatological Research” This study found that peripilar signs on the scalp are linked to perifollicular lymphocytic infiltrates in early androgenetic alopecia, detectable even in areas with high hair density.
52 citations
,
December 2014 in “Journal of Dermatological Science” Apremilast may help treat hair loss in alopecia areata.
13 citations
,
March 2020 in “Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy” This study used infrared spectroscopic imaging and scanning electron microscopy to reveal that alopecic hair has more irregular laminated structures and differing chemical profiles than normal hair, suggesting changes related to alopecia progression.
3 citations
,
May 2025 in “Carbohydrate Polymers” In this study, researchers developed a dissolvable microneedle patch containing baricitinib for alopecia areata treatment, reporting significantly higher hair growth in mouse models compared to controls, suggesting its potential as an effective, pain-free topical therapy.
This study found significant cephalometric changes in patients with skeletal Class III malocclusion treated with rapid maxillary expansion and reverse traction, demonstrating maxilla advancement and improved facial convexity.
29 citations
,
October 2012 in “Anais Brasileiros De Dermatologia” This review presents an objective analysis of female androgenetic alopecia, discussing clinical and dermoscopic examination approaches but reports no new clinical findings.
This study reported that acupuncture combined with topical Aloe vera and celery gel reduced hair loss from alopecia androgenetica after 28 days of treatment.
April 2013 in “Anais Brasileiros de Dermatologia”
22 citations
,
June 2013 in “Australasian Journal of Dermatology” Early stage bald spots are linked to skin inflammation and damage to the upper part of the hair follicle.
In this case study, a 65-year-old male with androgenetic alopecia showed slight hair growth after treatment with a Derma Roller System and Capillary Therapy.