65 citations,
March 2018 in “Journal of Dermatological Science” Skin problems can be caused or worsened by physical forces and pressure on the skin.
1 citations,
January 2021 This study focused on identifying and characterizing CD4+ non-haematopoietic, skin-resident cells and their role in skin homeostasis and tumorigenesis, particularly in basal cell carcinoma (BCC). The researchers used lineage-tracing, transcriptome sequencing, and flow cytometry to analyze potential CD4+ precursors in murine and human skin. They found that rare stem cell-like epidermal cells in the interfollicular epidermis (IFE) and infundibulum are likely candidates for BCC precursor cells. These CD4+ cells were shown to proliferate with age and wound healing in mice and possess similar stem cell-like characteristics in human skin. However, the exact origin of these cells remains uncertain due to limitations in investigative methods.
2 citations,
July 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Autophagy changes the protein makeup of hair.
1 citations,
September 2019 in “Journal of Investigative Dermatology” The research showed that CRISPR/Cas9 can fix mutations causing a skin disease in stem cells, which then improved skin grafts in mice, but more work on safety and efficiency is needed.
September 2019 in “Journal of Investigative Dermatology” Specialized ribosomes affect aging in human skin cells.
17 citations,
September 2017 in “Journal of Cosmetic Dermatology” Women with PCOS in North China often have hirsutism and acne, with hirsutism linked to metabolic issues.
3 citations,
September 2021 in “EClinicalMedicine” The study investigated protein expression in forehead epidermal corneocytes to distinguish between frontal fibrosing alopecia (FFA) and androgenetic alopecia (AGA). Samples from 5 FFA patients, 5 AGA patients, and 12 controls revealed that FFA had 72 proteins significantly different from controls, with most showing lower expression, while AGA had only 3 proteins significantly different. This suggests FFA affects protein expression systemically, beyond the scalp. The findings support non-invasive monitoring of FFA through forehead epidermis protein profiling, indicating a potential for better diagnosis and treatment monitoring.
January 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Aging affects the cells around hair follicles, which may influence female pattern hair loss and treatment options.
October 2023 in “Dermatology practical & conceptual” Hair loss might be linked to eye aging due to inflammation markers in blood.
9 citations,
April 2005 in “PubMed” Older female squirrel monkeys often experience a type of hair loss similar to chronic telogen effluvium in humans.
39 citations,
October 1967 in “British Journal of Dermatology” Hair loss in women often doesn't follow a pattern, isn't linked to age, may be genetic, and can be related to thyroid issues or other health factors.
86 citations,
July 2002 in “Clinical and Experimental Dermatology” FPHL is a common, age-related, genetic hair loss with unclear causes and limited treatment options.
Older women's scalp cells show changes that could contribute to hair thinning.
688 citations,
June 2007 in “Cell Stem Cell” Removing the ATR gene in adult mice causes rapid aging and stem cell loss.
1 citations,
May 2017 in “Asian journal of medical sciences” The dietary supplement significantly improved skin, nails, and hair in older adults.
1 citations,
May 2023 in “Frontiers in Endocrinology” Autism's genetics are linked with early age of puberty and less hair loss, but not with hormone levels or polycystic ovary syndrome.
January 2023 in “Dermatologica Sinica” Sex hormones affect hair growth and loss, and treatments for related hair diseases include various medications, hair transplantation, and light therapy.
April 2018 in “Journal of Investigative Dermatology” Older hair follicle stem cells have a reduced ability to renew themselves, leading to more hair loss.
24 citations,
November 2015 in “Frontiers in Genetics” Nitroxide drugs can safely and effectively treat age-related diseases like macular degeneration and cardiovascular issues.
January 2019 in “Cell & developmental biology” 3D cultivation and prenatal stem cell exosomes improve stem cell treatment results, especially for hair loss and age-related issues.
1 citations,
January 2021 in “British Journal of Dermatology” Caffeine may protect hair follicles from stress-related hair loss.
24 citations,
September 2012 in “Dermatologic Surgery” The conclusion is that normal scalp hair counts for Taiwanese people were established, showing age-related differences but not sex or scalp location differences.
35 citations,
October 2012 in “Dermatologic Clinics” Autoimmune diseases can cause hair loss, and early treatment is important to prevent permanent damage.
4 citations,
December 2020 in “International journal of research - granthaalayah” Tetracycline can stick to hair follicles and potentially cause hair loss.
October 2023 in “Dermatology practical & conceptual” Many patients experienced hair loss after COVID-19, with women affected more, starting on average 49 days post-infection.
January 2019 in “Elsevier eBooks” The most common cause of hair loss in children is tinea capitis, followed by alopecia areata and telogen effluvium.
20 citations,
July 2020 in “Experimental Dermatology” Aging scalp skin contributes to hair aging and loss, and more research is needed to develop better hair loss treatments.
November 2011 in “Informa Healthcare eBooks” Environmental, chemical, mechanical, and personal health factors can all damage hair and contribute to hair loss or changes in hair quality.
3 citations,
February 2022 in “Dermatology practical & conceptual” The study concludes that early diagnosis of Frontal Fibrosing Alopecia is important, as it is often found in postmenopausal women, may be related to Lichen Planopilaris, and eyebrow hair loss is a common sign.