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This review compiles existing information on the pathogenesis of androgenetic alopecia, highlighting its genetic, hormonal, and environmental factors, but reports no new clinical findings.

This study describes "alarm reaction" histologic changes in pilosebaceous structures, including regression of hair matrix and alterations in sebaceous glands, affecting follicular and sebaceous gland morphology.

This study introduces a hypothesis that elevated DHT at puberty may cause chronic thermal stress in specific scalp areas, potentially explaining Androgenetic Alopecia characteristics and guiding future research.

This study found that in vitro, beard dermal papilla cells stimulated keratinocyte proliferation via androgen-dependent growth factors, while androgenetic alopecia cells released TGF-β1, inhibiting keratinocyte growth.

This study found that in alopecia areata, hair bulbs are blocked in an early growth stage due to impaired metabolic function in the surrounding connective tissue, hindering hair growth.

Hidradenitis suppurativa improves with antiandrogen therapy.

In this study, researchers found that androgen receptor expression and AKR1C-mediated androgen inactivation, including AKR1C4, are prominent in scalp sebaceous glands, with AKR1C expression decreasing with age and differing by sex, suggesting these changes may impact hair follicle health as people age.

In a clinical case study, researchers identified adrenocortical adenoma as the cause of hyperandrogenism syndrome in a preschool-aged girl, following a comprehensive diagnostic process and successful surgical intervention to remove the tumor, leading to positive clinical improvements.

This study demonstrated that human sebaceous glands can be successfully transplanted onto nude mice, where androgen stimulation increases gland volume, cell size, and labeling index.

In this case report, a 35-month-old girl with loose anagen hair syndrome experienced spontaneous resolution and hair regrowth within 24 months.

This study outlines the clinical features of androgenetic alopecia in Korean adolescents, finding milder symptoms compared to adults and a high occurrence of family history, with normal hormone levels.

This study suggests that the newly characterized sebocytic progenitor cells HSGC1 and HSGC2 from different skin sites may have proliferative and differentiating potential in response to DHT.

Merkel cells are abundant in facial vellus hair follicles, especially during the anagen phase.

This case report describes a newly identified condition called loose anagen hair of childhood, characterized by easily pluckable hair in two young boys, with variable duration and no scalp inflammation or scarring.

This study identified a distinct "exogen" phase in the hair cycle during which hair shedding occurs, primarily coupled with the anagen phase, rather than as part of the telogen phase.

This study found that androgen inactivation pathways in scalp sebaceous glands change with age, specifically noting that AKR1C expression, including AKR1C4 previously thought liver-specific, declines with age and is sex dependent, which could impact hair follicle health during aging.

This case study describes a 15-year-old girl with progressive hair thinning and reduced hair density at the frontal scalp, with a family history of alopecia.

This study found that estradiol affects hair growth in mice by regulating the transition of hair follicles from rest to growth phases via the estrogen receptor pathway in the dermal papilla.

This study found that increased expression of type II 5α-reductase, androgen receptors, and Hic-5/ARA55 in dermal papilla cells upregulates androgen sensitivity, playing a key role in androgenetic alopecia pathogenesis.

In this study, researchers found that the thyroxine receptor agonist TDM10842 accelerated the onset of anagen, a hair growth phase, in C3H mice, potentially through activation of the Wnt/beta-catenin and Hedgehog pathways, with Pclaf playing a key role in this process.

This article reviews anagen effluvium, a type of non-scarring alopecia that affects both men and women, often induced by chemotherapy or radiation, and discusses diagnostic approaches but reports no new clinical findings.

In this abstract, the issue of "microinflammation" in hair follicles, central to androgenetic alopecia, is described as involving an inflammatory process with Langerhans cells and keratinocytes presenting antigens to T lymphocytes, leading to an immune response with macrophages or natural killer cells destroying these antigens.

This review discusses various hormonal and neuropeptide influences on hair growth and reports no new clinical results; it highlights complexity and suggests areas for future exploration.

This study found that a high dose of epidermal growth factor induced hair loss in sheep by causing apoptosis in anagen hair and transitioning the hair cycle to catagen.

In this case study, a six-year-old girl was diagnosed with isolated adrenarche, linked to premature adrenal maturation, with increased dehydroepiandrosterone sulfate and axillary and pubic hair growth, and will require long-term monitoring due to increased risks of conditions like polycystic ovary syndrome and cardiovascular diseases.

This case study reports a rare instance of mucinous cystadenoma causing severe virilization in a postmenopausal woman, highlighting a possible link with rapidly progressive hyperandrogenism.

This article reviews the hormonal pathogenesis of acne vulgaris and androgenetic alopecia, emphasizing various hormonal factors beyond androgens, but reports no new clinical findings.

This study reported that EGFR activation leads to suppression of Stathmin, which may promote synchronized entry into catagen in hair follicles, highlighting potential mechanisms involving EGFR in hair cycle transitions.