Alarm Reaction of Pilosebaceous Apparatus
July 1979
in “
Journal of the American Academy of Dermatology
”
Studysummary This study describes "alarm reaction" histologic changes in pilosebaceous structures, including regression of hair matrix and alterations in sebaceous glands, affecting follicular and sebaceous gland morphology.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The document described a series of histologic changes in the pilosebaceous structures termed as an "alarm reaction." This reaction was characterized by the regression of the hair matrix, leading to the formation of a nest of small basaloid cells within the follicular canal. Additionally, the sebaceous glands either became undifferentiated, forming a solid mass of stratified squamous epithelium, or the sebaceous lobules were incorporated into the follicular canal and surface keratin layer.