Alarm Reaction of Pilosebaceous Apparatus

    Amir H. Mehregan
    Studysummary This study describes "alarm reaction" histologic changes in pilosebaceous structures, including regression of hair matrix and alterations in sebaceous glands, affecting follicular and sebaceous gland morphology.
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    The document described a series of histologic changes in the pilosebaceous structures termed as an "alarm reaction." This reaction was characterized by the regression of the hair matrix, leading to the formation of a nest of small basaloid cells within the follicular canal. Additionally, the sebaceous glands either became undifferentiated, forming a solid mass of stratified squamous epithelium, or the sebaceous lobules were incorporated into the follicular canal and surface keratin layer.
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