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The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

New effective scar treatments are urgently needed due to the current options' limited success.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Some medicinal plants can help heal wounds and may lead to new treatments.

Minoxidil sulfate stimulates hair growth.

Some people with pattern hair loss may also have scalp inflammation and scarring similar to lichen planopilaris.

Lichen planus is a skin condition that can resolve on its own, is linked to hepatitis C, and increases the risk of skin cancer.

Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

Superficial granulomatous pyoderma is a unique, mild form of skin disease that often heals without strong medication and responds well to milder treatments.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Low oxygen conditions increase the hair-growing effects of substances from fat-derived stem cells by boosting growth factor release.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

No single treatment is consistently effective for alopecia areata, and more research is needed.