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Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Guidelines for diagnosing common hair loss include detailed history, clinical examination, and various diagnostic techniques.

Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Bioprinting could improve wound healing but needs more development to match real skin.

Peptide hydrogels heal burn wounds faster and better than standard dressings.

Estrogen therapy can reduce skin aging but has cancer risks.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

Stem cell self-renewal is complex and needs more research for full understanding.

Women with PCOS have a higher risk of diabetes and heart problems, especially when they get older.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Scalp dermoscopy is good for diagnosing a type of hair loss and helps choose the best spots for biopsy.

Antiandrogens are somewhat effective in reducing excessive hair growth in women.

About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.

Proper haircare and communication with doctors are key to managing hair loss and avoiding damage.

Laser hair removal effectiveness depends on targeting hair structures without harming the skin, and improvements require more research and expert collaboration.

Palliative chemotherapy is cost-effective for advanced gastric and colorectal cancer but not clearly for pancreatic-biliary cancer.

Mouse Notch is important for determining cell roles in hair follicles.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Targeted cancer therapies often cause skin side effects, needing dermatologist care.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

miR-31 regulates hair growth by controlling gene expression in hair follicles.

Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

Minoxidil boosts hair growth by increasing cell production and survival.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Minoxidil works better for female hair loss, but cyproterone reduces scalp oiliness and causes menstrual issues.