57 citations
,
July 2018 in “Scientific Reports” This study found that prevascularizing dermal matrices with adipose tissue-derived microvascular fragments improved vascularization and allowed earlier successful skin grafting in a bradythrophic wound model.
51 citations
,
September 2020 in “Cell Metabolism” This study highlights that the mammalian target of rapamycin complex 2 (mTORC2)-Akt signaling axis is essential for hair follicle stem cells to return to their niche and regenerate effectively by regulating metabolic pathways.
43 citations
,
September 2017 in “Lasers in Surgery and Medicine” This study found that LED light irradiation induced proliferation and migration of human outer root sheath cells, potentially through the stimulation of the Wnt/β-catenin and ERK signaling pathways.
39 citations
,
June 2017 in “Scientific Reports” Different lab conditions and light treatment methods change how human skin cells respond to light therapy.
37 citations
,
February 2007 in “Clinical Obstetrics and Gynecology” This article examines current pharmacologic treatments for PCOS focusing on symptom-specific approaches, particularly the metabolic effects of therapies, but reports no new clinical findings.
36 citations
,
April 2016 in “Experimental Dermatology” This review discusses the challenges in selecting optical parameters for photobiomodulation studies on hair regrowth and wound healing, reporting no new clinical results and recommending more rigorous, standardized research approaches.
27 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This article explores the endocrine functions involved in the pathogenesis of polycystic ovarian syndrome and discusses approaches for diagnosing and managing the condition, with no new clinical results reported.
27 citations
,
December 2001 in “Clinical and experimental dermatology” This review discusses various hair removal methods, including physical, hormonal, and laser treatment, providing an overview of their advantages and disadvantages without presenting new clinical findings.
24 citations
,
July 2017 in “Structure” In this study, researchers found that ligand homodimerization controls the receptor binding specificity of the FGF9 subfamily, preventing off-target activation of FGFR "b" isoforms.
21 citations
,
January 2019 in “Lasers in Medical Science” This review found that low-level laser therapy significantly increased hair density in adults with androgenic alopecia compared to sham treatments, with greater effects observed at lower treatment frequencies.
17 citations
,
December 2015 in “International Journal of Cosmetic Science” This review discusses the effectiveness of non-thermal, non-ablative devices like light-emitting diodes in treating various skin and hair conditions but reports no new clinical findings.
16 citations
,
September 2018 in “Journal of Molecular Liquids” This study investigated a nanostructured system using PS-b-PAA diblock copolymer for incorporating the hydrophobic photosensitizer ClAlPc, finding it effective in causing cellular damage in Caco-2 cells under light while demonstrating no cytotoxicity without light, suggesting its potential use in photodynamic therapy.
15 citations
,
February 2008 in “Annals of plastic surgery” In this study, 80% of patients expressed satisfaction with diode-laser hair removal, though multiple treatments were needed for optimal results and were a deterrent for some.
14 citations
,
March 2012 in “Lasers in Surgery and Medicine” This study concluded that low-level fluence 810 nm diode laser therapy was generally well tolerated, safe, and effective for long-term hair reduction in a small sample of patients with various skin types.
13 citations
,
June 2020 in “BMC genomics” This study found that chi-miR-30b-5p was more expressed in the telogen phase than in the anagen phase and inhibited dermal papilla cell proliferation by targeting CaMKIIδ.
11 citations
,
October 2020 in “Sensors” This study found that photoacoustic imaging can effectively measure follicle density and angles, even when follicles are not visible to the eye, providing a promising alternative to traditional photographic examination.
9 citations
,
October 2022 in “Nature Communications” In this study, researchers developed a new photoactivatable Cre recombinase mouse model, DiLiCre, which allows precise light-induced genetic modifications and cell tracing, demonstrating its effectiveness for advancing biological and biomedical research.
8 citations
,
November 2020 in “Optics and Laser Technology” This review discusses the applications and advantages of LED-based photobiomodulation therapy for dermatological and cosmetic purposes but highlights existing challenges and health concerns while exploring future perspectives.
5 citations
,
March 2018 in “Advances in integrative medicine” This case report describes a novel integrative treatment approach leading to symptom improvement and significant reduction of thyroid antibodies in a young woman with Hashimoto’s thyroiditis.
4 citations
,
October 2009 in “Skin research and technology” This study found that tristimulus colorimetry is a sensitive and quantitative method for projecting hair growth rates in depilated mice, and it observed that 890 nm LED irradiation promotes hair regrowth.
3 citations
,
July 2011 in “Expert Review of Dermatology” This article reviews the causes and treatments of hirsutism, emphasizing the importance of considering ethnic and cultural norms when interpreting grading systems, and reports no new original findings.
2 citations
,
May 2010 in “Actas Dermo-Sifiliográficas” This article reviews home-use laser and intense pulsed light systems for hair removal and growth, noting limited efficacy and safety data and emphasizing the need for long-term studies.
1 citations
,
September 2025 in “Cureus” In this study, the ChatGPT-5 model accurately answered 76.47% of questions on the Polish endocrinology specialty exam, surpassing the 60% passing threshold, yet its role in clinical decision-making remains uncertain, highlighting the need for further research.
1 citations
,
March 2024 in “Brain Imaging and Stimulation” This study reported that a 3D-printed LED photobiomodulation device is technically and financially feasible, but requires further experimental and clinical testing before being used in human healthcare.
1 citations
,
November 2023 in “Journal of Cutaneous and Aesthetic Surgery” This study found that diode laser effectively reduces unwanted facial hair in darker skin types and reported no serious adverse events, suggesting that trichoscopy is an underutilized tool for assessing laser hair reduction outcomes.
1 citations
,
November 2023 in “Clinical, cosmetic and investigational dermatology” In this review, researchers examined the current status and advancements in using long-pulse alexandrite lasers for treating hair removal, vascular lesions, and pigmented lesions, aiming to guide clinical use based on how the laser's 755nm wavelength is absorbed by melanin and hemoglobin.
1 citations
,
July 2020 in “Dermatology” This review discusses the mechanisms, applications, and research evidence of photobiomodulation, highlighting its efficacy, safety, and potential for standardized evaluation methods, but reports no new clinical results.
1 citations
,
January 2009 in “Elsevier eBooks” This chapter reviews techniques for treating pseudofolliculitis barbae and suggests that combining daily shaving with topical treatments like glycolic acid may effectively manage this condition without new clinical results reported.
July 2026 in “Journal of the Pakistan Medical Association” This study found that combining topical eflornithine with triple diode laser treatments in women with hirsutism led to a more rapid and nearly complete reduction of terminal hair after 6 months, though the intergroup differences were not significant at 6- and 12-month follow-ups.
June 2026 in “Ophthalmology and Therapy” This review concluded that near-infrared and red light photobiomodulation shows potential for certain ocular conditions like age-related macular degeneration and dry eye disease, but clinical evidence is still mixed and insufficient to establish it as a standard therapy.