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Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

Compound 15a was effective in inhibiting 5α-reductase.

Dutasteride effectively and safely treats male hair loss for over a year.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

5-alpha reductase inhibitors may reduce bladder cancer recurrence and improve survival.

Taking 5-alpha reductase inhibitors does not increase the risk of breast cancer in men.

Nanostructured delivery systems could potentially improve hair loss treatment by targeting drugs to hair follicles, reducing side effects and dosage, but the best size, charge, and materials for these systems need further investigation.

Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.

Finasteride may affect PNMT, causing side effects.

Connarus semidecandrus Jack extract promotes hair growth and thickness, reduces prostate cancer cell growth, and could potentially be used as a treatment for hair loss.

Oral finasteride and dutasteride may negatively affect erectile function in rats.

Melandrium firmum extract helps mice grow hair by blocking a hair loss enzyme and changing hair growth genes.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

The document concludes that women should not use 5-alpha-reductase inhibitors due to the risk of birth defects and limited effectiveness.

Bitter melon extract may help prevent hair loss and can be used in cosmetic products.

Dutasteride and finasteride can help increase hair growth gene expression but need further improvement.

5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.

Low-dose dutasteride effectively and safely promotes hair growth in men with androgenetic alopecia.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Nanocarrier-based treatments show promise for better hair growth in androgenetic alopecia but need more research.

Finasteride harms Daphnia magna's reproduction, growth, and metabolism.

5-alpha-reductase inhibitors lower PSA density but higher PSA density indicates disease progression.

Solanum nigrum may help treat hair loss.

Finasteride may help reduce anxiety and depression in elderly but might cause depression in young men.

Long-term use of a drug for hair loss and prostate issues can cause metabolic problems and depression-like behavior in young male rats.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Finasteride and dutasteride are effective in treating male hair loss but can cause sexual side effects and birth defects.

5-Alpha Reductase Inhibitors are effective for male hair loss and some skin conditions, but their effectiveness in women and safety concerns require careful use.

Eclipta alba extract could be a promising natural treatment for hair loss.

Androgen treatment with dihydrotestosterone may help maintain height in patients with 5-α-reductase type 2 deficiency, especially before puberty.