Search

everythinglearnresearchcommunity

for

Search:↓

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

Men taking 5-alpha-reductase inhibitors before or after bladder cancer diagnosis had a lower risk of dying from the disease.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Glioblastoma cells can make androgens, which might help the tumor grow.

5-alpha reductase inhibitors might worsen lung recovery in COVID-19 patients, suggesting a pause in their use.

Finasteride reduces movement issues in Parkinson's disease rats.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.

Some common medications can harm male fertility, but many effects can be reversed.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

New steroids were effective in blocking male hormone receptors in hamster prostates.

Use antiandrogens and other treatments for hair loss.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.