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Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Nanoencapsulation creates adjustable cell clusters for hair growth.

The research found different metabolism changes in PCOS patients and suggested new potential markers for diagnosing PCOS with or without insulin resistance.

Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

Short-term finasteride treatment may lower some cell death factors in prostate cancer cells.

Scientists have created a method to deliver specific cells that can regenerate hair follicles, potentially offering a new treatment for hair loss.

Rabbits lacking the Hoxc13 gene show similar hair and skin issues to humans with ECTD-9, making them good for research on this condition.

Testosterone helps human pancreatic cells increase insulin release.

Dutasteride works better than finasteride for preventing and treating prostate cancer.

Using 5-butylpicolinate esters improves the sensitivity and reliability of detecting testosterone and dihydrotestosterone in saliva.

Deleting the p63 gene in certain cells causes problems in thymus development and severe hair loss in mice.

The study found that combining SHG and OCT effectively monitors skin wound healing in mice.

Eclipta alba L. (Urang-Aring) can help treat hair loss.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.