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TET enzymes are important for skin and hair development by controlling gene activity in specific areas.

The enzymes Tet1, Tet2, and Tet3 are important for the development of hair follicles and determining hair shape by controlling hair keratin genes.

Tet1/2/3 enzymes affect hair follicle cell development by influencing BMP signaling.

Stem cells control their future role by changing ERK signal timing, affecting tissue regeneration and cancer.

Mouse skin glands need healthy nerves to grow properly during hair growth phases.

Hair follicles repair 3D injuries using a 2D healing process.

Cyclooxygenase-2 overexpression in mice skin causes hair loss like human androgenetic alopecia.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

The enzymes Tet2 and Tet3 are important for skin cell development and hair growth.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Tissue environment greatly affects the unique epigenetic makeup of regulatory T cells, which could impact autoimmune disease treatment.

5% minoxidil works better for hair growth and density, with minor irritation.

Drugs that block DHT production can effectively treat enlarged prostate and improve urinary issues with some sexual side effects.

5% and 2% minoxidil solutions effectively promote hair growth and reduce hair loss, with 5% being slightly more effective but having more side effects.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

5α-reductase inhibitors may prevent prostate cancer but could also raise the risk of more severe cancers.

New 5% minoxidil foam effectively promotes hair growth and is safe for use.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Testosterone's muscle-building effects do not require its conversion to DHT.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

5% minoxidil foam once daily works as well as 2% minoxidil solution twice daily for female hair growth and is more convenient.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

The treatment combining docetaxel, cisplatin, and 5-FU is feasible and effective for advanced head and neck cancer.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

Finasteride works better than Permixon in reducing dihydrotestosterone levels.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.