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The study created a new method to test drugs that affect hormone processing in skin.

Finasteride affects the male rat brain by reducing certain protein activation, but these effects may reverse after stopping the drug.

Eclipta alba extract could be a promising natural treatment for hair loss.

Computational methods can speed up and improve the development and safety of herbal drugs.

Hair loss in women, often not related to male hormones, increases with age and can cause significant emotional distress.

Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.

Androgenetic alopecia, or hair loss, is caused by a mix of genetics, hormones, and environment, where testosterone affects hair growth and causes hair to become smaller and grow for a shorter time.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

Bitter melon extract may help prevent hair loss and can be used in cosmetic products.

A new plant extract from Avicennia marina could potentially be used to treat common hair loss.

An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

Avicequinone C, a compound found in the Avicennia marina plant, can reduce hair loss by inhibiting a hormone linked to androgenic alopecia.

Finasteride may affect PNMT, causing side effects.

The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

Ganoderma lucidum, a type of mushroom, may help treat enlarged prostate by blocking testosterone conversion.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride is a safe, effective treatment for hirsutism with fewer side effects.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

Minoxidil effectively treats hair loss, especially androgenetic alopecia, but needs more research for better understanding.

Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.

Ahmad's NPRT system accurately documents and predicts male pattern baldness.

Plant-based chemicals may help hair growth and prevent hair loss but need more research to compete with current treatments.

5% minoxidil works better for hair growth and density, with minor irritation.

Drugs that block DHT production can effectively treat enlarged prostate and improve urinary issues with some sexual side effects.

5% and 2% minoxidil solutions effectively promote hair growth and reduce hair loss, with 5% being slightly more effective but having more side effects.

5α-reductase inhibitors may prevent prostate cancer but could also raise the risk of more severe cancers.

New 5% minoxidil foam effectively promotes hair growth and is safe for use.