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Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

Hair loss drugs like finasteride may cause lasting sexual and mood side effects, and more research is needed to understand these risks.

An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

Testosterone's muscle-building effects do not require its conversion to DHT.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.

Women with non-classical congenital adrenal hyperplasia have higher levels of certain steroids, which can be reduced by treatment.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.

New tests detect finasteride and dutasteride in urine quickly and easily.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

DHT, a testosterone byproduct, causes male pattern baldness.

Finasteride may cause lasting sexual and mental health issues, and genetic screening could help prevent them.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

The compounds tested could potentially treat hair loss and alopecia.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

A combination of desogestrel and ethinyl oestradiol effectively reduces hair growth in hirsute women.

Using K2S2O8 as an oxidizing agent in a specific condition, we can make Finasteride with 96.3% yield and 99.6% purity. This method is also good for other compounds and is environmentally friendly.

Spironolactone reduced hair thickness and some testosterone levels in women with excessive hair growth.

Oophorectomy lowers testosterone and estrogen levels in both premenopausal and postmenopausal women, with postmenopausal women still producing significant testosterone.

Dutasteride makes alcohol less sedating and may lead to less drinking in men.

Finasteride helps reduce prostate size and symptoms in BPH but is less effective than terazosin and works best for larger prostates.