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Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Alopecia X in dogs is a cosmetic issue, not a hormonal disorder, and harmful treatments should be avoided.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

SHBG may be a useful early indicator and treatment target for PCOS.

Finasteride works better than Serenoa repens for male hair loss.

Diane 35 plus finasteride is more effective in reducing hair growth and androgen levels, but may decrease libido.

DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.

New compounds can block testosterone effects in rats and might help treat conditions like prostate cancer and acne.

Finasteride can cause enlarged breasts.

Indigofera tinctoria leaf extract has many compounds that support its traditional medicinal uses.

The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.

AGA is a genetic, hormonal hair loss treated with finasteride, minoxidil, and supplements, but new compounds are being developed.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Finasteride improves immune response and reduces organ damage after trauma hemorrhage in mice.

Eating high-glycemic and dairy foods can increase hormones that may cause acne and other health issues.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.

The document concludes that managing female hyperandrogenism requires a combination of identifying the cause, lifestyle changes, medication, and cosmetic treatments.

Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.

Skin problems in PCOS, like excess hair, acne, and hair loss, may not always indicate high male hormone levels and need careful diagnosis for proper treatment.