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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.

New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Dutasteride is more efficient than finasteride, but individual results vary.

12-Methoxy carnosic acid from rosemary might be a good natural treatment for hair loss.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.

Some plant-based products might treat hair loss with fewer side effects than current medications.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.

Dutasteride improved both hair loss and acne in two young men.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.

Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

Pumpkin seed products may help improve prostate and bladder health by blocking certain enzymes and hormone receptors.

Finasteride, when taken daily, lowers dihydrotestosterone levels but doesn't noticeably affect adrenal steroid production, except by blocking the 5 alpha-reductase enzyme.

Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.

The herbal hair cream could help treat male pattern baldness by blocking a baldness-related enzyme and might be worth further investigation.

Young and adult hamsters both respond similarly to testosterone and finasteride treatments, but young hamsters aren't good for testing the inhibitory activity of a specific enzyme.

The seed extract of Lepidium sativum L. can potentially treat hair loss, showing effects similar to 5% minoxidil.

Betula platyphylla extract, particularly the H3-2 fraction, may help treat hair loss by promoting cell growth and inhibiting a hair loss-related enzyme.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.

Nanoliposomes loaded with saw palmetto extract could be good for treating hair loss.