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The document suggests that drugs for prostate issues might cause lasting sexual, mental, and physical health problems due to blood vessel damage in the penis.

Medicines called 5-alpha-reductase inhibitors, like finasteride and dutasteride, are useful for treating enlarged prostate and male pattern hair loss.

5-alpha reductase inhibitors may have additional effects on cancer, mental health, heart health, and hormone levels beyond treating prostate enlargement.

5-alpha reductase inhibitors like finasteride and dutasteride are effective for treating enlarged prostate and male pattern hair loss.

5-alpha-reductase inhibitors significantly affect the penile tissue of hypertensive rats.

5-alpha reductase inhibitors slightly reduce urinary symptoms and may lower surgery and acute retention risks in men.

Finasteride effectively treats hair loss and prostate issues with minimal side effects.

Men with hair loss who take a certain type of medication may experience fewer COVID-19 symptoms.

Dutasteride and finasteride can change hair growth genes, helping treat hair loss.

Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Black pepper leaf extract contains compounds that can block testosterone effects and promote hair growth.

Taking finasteride pills and using minoxidil lotion together can help grow hair.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Some plant-based products might treat hair loss with fewer side effects than current medications.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.

Men taking 5-alpha-reductase inhibitors before or after bladder cancer diagnosis had a lower risk of dying from the disease.