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EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

A simple screening method found that 6.3% of women in a semiurban area in Sri Lanka have polycystic ovary syndrome, with most showing menstrual irregularities.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

Aminopterin strongly suppresses epithelial tissues and can treat certain skin conditions but has significant side effects.

Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

Hair follicle regeneration needs special conditions and young cells.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

Adult human skin can grow new fine hair follicles after a deep exfoliation treatment.

The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

The EpiLight Hair Removal System removed about 60% of hair with some side effects, and more research is needed to confirm long-term effectiveness.

PHBV nanofiber matrices help wounds heal faster when used with hair follicle cells.

Sub3 is essential for fungus adherence but not for skin invasion.

Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.

CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.

EGF and FGF boost hair cell growth, hydrocortisone slows it, and minoxidil doesn't affect it.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Mice with human skin protein K8 had more skin problems and cancer.

α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.

Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.

Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.

Three new types of a skin blistering disease were found, caused by specific gene mutations.

Ephrins slow down skin and hair follicle cell growth.