research Metabolism of Minoxidil, a New Hypotensive Agent: Biotransformation Following Oral Administration to Rats, Dogs, and Monkeys
Minoxidil metabolizes similarly in monkeys and humans, but differently in dogs and rats.
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research Androgen Receptor in Human Health: A Potential Therapeutic Target
The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.
research A Review on Hydrogels with Photothermal Effect in Wound Healing and Bone Tissue Engineering
Photothermal hydrogels are promising for infection control and tissue repair, and combining them with other treatments could improve results and lower costs.
research Advances in Nucleoside Monophosphate Prodrugs as Anti-HCV Agents
New treatments for Hepatitis C show promise but need more research to confirm their safety and effectiveness for clinical use.
research Cutaneous Androgen Metabolism: Basic Research And Clinical Perspectives
Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.
research Cannabinoids: Current and Future Options to Treat Chronic and Chemotherapy-Induced Neuropathic Pain
Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.
research Polyamines and Hair: A Couple in Search of Perfection
Polyamines are important for hair growth, but more research is needed to understand their functions and treatment potential.
research Molecular Docking Studies and ADME Prediction of Novel Isatin Analogs with Potent Anti-EGFR Activity
Some new isatin compounds could be strong cancer-fighting drugs because they fit well in cancer-related proteins and have good drug-like properties.
research Androgen Receptor Antagonists Structure-Activity Relationships
Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.
research Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle
Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.
research Pharmacological Activity Of Cepharanthine
Cepharanthine has many medicinal uses but needs improvement for better effectiveness.
research Notch Signaling Is Significantly Suppressed in Basal Cell Carcinomas and Activation Induces Basal Cell Carcinoma Cell Apoptosis
Activating Notch signaling can kill basal cell carcinoma cells.
research Simultaneous Quantitation of Nine Hydroxy-Androgens and Their Conjugates in Human Serum by Stable Isotope Dilution Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry
A new method accurately measures nine specific hormones in human blood.
research Strategies for Improved Hair Binding: Keratin Fractions and the Impact of Cationic Substructures
Certain treatments can increase protein binding to natural hair but are less effective on permed hair.
research The Acyl-CoA Binding Protein Is Required For Normal Epidermal Barrier Function In Mice
ACBP is crucial for healthy skin in mice.
research A Guide to the Use of Bioassays in Exploration of Natural Resources
Bioassays help find useful compounds in nature for making medicines, supplements, and cosmetics.
research Epidermal Stem Cells Do Not Communicate Through Gap Junctions
Epidermal stem cells don't use gap junctions to communicate.
research Ethnodermatological Use of Medicinal Plants in India: From Ayurvedic Formulations to Clinical Perspectives – A Review
Indian herbal medicine shows promise for treating skin diseases but needs more research to prove effectiveness.
research Attempted Construction of Minoxidil: Carboxylic Acid Cocrystals; 7 Salts and 1 Cocrystal Resulted
Made 8 minoxidil samples; 1 cocrystal, 7 salts formed.
research Novel Inhibitors of 5α-Reductase
New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
research Androgen Receptor Modulators: A Review of Recent Patents and Reports (2012-2018)
New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.
research Floral Attractants in the Black Orchid Brasiliorchis Schunkeana: Clues for Presumed Sapromyophily and Potential Antimicrobial Activity
The black orchid Brasiliorchis schunkeana produces chemicals that attract certain insects and have potential antimicrobial properties.
research Baiting Proteins with C60
C60 fullerenes can alter protein function and may help develop new disease inhibitors.
research Mechanical and Biological Properties of Keratose Biomaterials
Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.
research HDL as Therapeutic Tools
Modified HDL can better deliver drugs and genes, potentially improving treatments and reducing side effects.
research Low-Molecular-Weight Synthetic Antioxidants: Classification, Pharmacological Profile, Effectiveness, and Trends
Synthetic antioxidants are effective, cheap, and stable, with some like zinc and cholecalciferol reducing child and cancer deaths, but the safety of additives like BHA, BHT, TBHQ, and PEG needs more research.
research Steroid Sulfatase Inhibitors: Therapeutic Applications and Development
Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.
research Sulfatase Inhibitors: A Patent Review
The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
research The Rotterdam Study: 2016 Objectives and Design Update
The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.
research ESGCT and FSGT Collaborative Congress Helsinki, Finland September 17–20, 2015 Abstracts
The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.