research Adverse Drug Reactions and Interactions: Case Studies
Some medications caused temporary health issues that improved after stopping the drugs, but two patients died from liver problems linked to carbamazepine.
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30-60 / 1000+ results research Regulatory Effects of Thai Rice By-Product Extracts from Oryza Sativa L. Cv. Bue Bang 3 CMU and Bue Bang 4 CMU on Melanin Production, Nitric Oxide Secretion, and Steroid 5α-Reductase Inhibition
BB4CMU rice bran oil may help treat hair loss and gray hair.
research Advances in Cosmetic Dermatology
The book provides an overview of new trends and techniques in cosmetic dermatology.
research Azasteroids as Inhibitors of Testosterone 5α-Reductase in Mammalian Skin
Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.
research Prevalence of Polycystic Ovary Syndrome in Unselected Black and White Women of the Southeastern United States: A Prospective Study
PCOS affects about 4% of women in the southeastern U.S. equally across Black and White populations.
research Defining Hyperandrogenaemia According to the Free Androgen Index in Chinese Women: A Cross-Sectional Study
FAI values above 6.4 may suggest high androgen levels and increased metabolic risks in Chinese women of reproductive age.
research The Effects of the COVID-19 Pandemic on the Dermatology Outpatient Clinic of Aydın Adnan Menderes University Hospital
COVID-19 reduced dermatology visits by 30.4%, with more male patients and increased cases of psoriasis, bullous diseases, and melanoma.
research The Optimal Holding Solution and Temperature for Hair Follicle Grafts
Best solution for storing hair grafts is saline with ATP at 4 degrees Celsius, but no definitive best method was confirmed.
research Hair Counts in Scalp Biopsy of Males and Females with Androgenetic Alopecia Compared with Normal Subjects
AGA patients have fewer hairs and smaller follicles; T:V ratio above 4:1 may indicate AGA.
research Acne Keloidalis Nuchae: Risk Factors and Associated Disorders – A Retrospective Study
The study suggests that acne keloidalis nuchae is linked to conditions like pseudofolliculitis barbae, scalp infections, metabolic syndrome, and is more common in males with an average onset age of 25.4 years.
research Contact Dermatitis to Phenol-Formaldehyde Resin in Two Plywood Factory Workers
Two plywood factory workers developed contact dermatitis from phenol-formaldehyde resin, a known allergen.
research Synthesis of Minoxidil Conjugates and Their Evaluation as HL-60 Differentiation Agents
Some minoxidil combinations can help differentiate leukemia cells without harming other cells.
research Alopecia Areata: Treatment Options and Efficacy
Some treatments can help with a hair loss condition called alopecia areata, but none ensure lasting results; choices depend on the person, with JAK inhibitors showing promise for severe cases.
research Regulatory T Cells: The Many Faces of Foxp3
Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.
research Four-Amino Acid Segment in Steroid 5 Alpha-Reductase 1 Confers Sensitivity to Finasteride, a Competitive Inhibitor
Four-amino acid part makes enzyme sensitive to finasteride.
research Androgen Binding Profiles of Two Distinct Nuclear Androgen Receptors in Atlantic Croaker (Micropogonias Undulatus)
Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.
research Clinical, Ultrasound, and Hormonal Markers of Androgenicity in Acne Vulgaris
Acne severity is linked to higher levels of certain androgenic hormones, even when those levels are within the normal range.
research Dupilumab: A Review of Present Indications and Off-Label Uses
Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.
research Minoxidil Specifically Decreases the Expression of Lysine Hydroxylase in Cultured Human Skin Fibroblasts
Minoxidil reduces lysine hydroxylase in skin cells.
research Lack of Efficacy of Apremilast in 9 Patients with Severe Alopecia Areata
Apremilast did not work for treating severe alopecia areata.
research Novel Inhibitors of 5α-Reductase
New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
research 5α-Reductase Inhibitors: Chemical and Clinical Models
Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.
research A Connection Between the Mitochondrial Permeability Transition Pore, Autophagy, and Cerebral Amyloidogenesis
Dutasteride may help reduce brain plaque linked to Alzheimer's by affecting cell energy structures and waste removal.
research Successful Treatment of Sebaceous Adenitis in a Rabbit with Ciclosporin and Triglycerides
A rabbit with sebaceous adenitis was effectively treated with ciclosporin and medium-chain triglycerides.
research Recent Advances in Drug Design and Drug Discovery for Androgen-Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
research Alopecia: The Search for Novel Agents Continues
Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.
research Selective Induction of Apoptosis in the Hamster Flank Sebaceous Gland Organ by a Topical Liposome 5-Alpha-Reductase Inhibitor: A Treatment Strategy for Acne
A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.
research Impaired Responses of Peripheral Blood Mononuclear Cells to T-Cell Stimulants in Alopecia Areata Patients with a Poor Response to Topical Immunotherapy
Poor response to topical immunotherapy in alopecia areata patients is linked to impaired cell responses.
research Follicular Unit Extraction: Advances and Challenges
FUE is a less invasive hair restoration method with potential to become standard, offering benefits like reduced scarring and pain, but requires experience to minimize risks.
research Epidermal Growth Factor Receptor Mutant T790M-L858R-V948R Inhibitor from Calophyllum Inophyllum L. Leaf as Potential Non-Small Cell Lung Cancer Drugs
A compound from Calophyllum inophyllum L. leaf may help treat non-small cell lung cancer.