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Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Hair loss in women can be slowed with treatment, but more research needed for better solutions.

Genetic mutations can affect female sexual development, requiring personalized medical care.

Indigofera tinctoria leaf extract has many compounds that support its traditional medicinal uses.

Androgen use may increase the risk of stroke, but more research is needed.

The conclusion is that new plant-based treatments for hair loss may work by targeting certain enzymes.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

The gel made of minoxidil and hydroxypropyl-β-cyclodextrin improves hair growth and is good for long-term use.

Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.

Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

Herbal formula shows promise for hair loss treatment.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

Higher testosterone harms sperm motility, while higher estradiol improves sperm survival.

Understanding genes and hormones is crucial for managing male puberty and sex development disorders.