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Testosterone replacement therapy should be used for men with low testosterone levels and symptoms of hypogonadism, after careful diagnosis and considering individual needs.

Plant extracts like Avicennia marina, Boehmeria nipononivea, and Camellia sinensis could potentially treat hair loss with fewer side effects than synthetic drugs.

Estrogen-progestin contraception lowers ovarian, endometrial, and colon cancer risk but may raise breast and cervical cancer risk, helps with menstrual and acne issues, and new methods are as effective as pills. Metformin helps overweight women with PCOS and insulin resistance, and dopamine agonists treat prolactinomas.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

The control system for hair growth cycles is not well understood and needs more research.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

Mice without the Sp6 gene have problems developing several body parts, including hair, teeth, limbs, and lungs.

Baricitinib for severe alopecia areata is generally safe, with common side effects like infections and acne, and low rates of serious complications.

Certain drugs change freshwater snail shells to a "banana" shape.

Small injections of dutasteride improved hair thickness in men with hair loss without major side effects.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Essential oils in cosmetics can offer benefits but may cause allergies and should be used carefully.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.

Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Skin problems in COVID-19 patients are rare and may be due to the body's complex immune response or blood clotting issues.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Both mouse and rat models are effective for testing alopecia areata treatments.

Human hair contains diverse proteins, including keratins and histones, which could help assess hair health and aging.

Some plants used in traditional medicine may help treat cancer because they contain proteins that can inactivate ribosomes.

Some plants with flavonoids may help treat hair loss and promote hair growth.

The leaves of Platycladus orientalis have potential health benefits but require more research for safety and understanding how they work.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Lanyu pigs show that partial-thickness wounds can partially regenerate important skin structures, which may help improve human skin healing.

The leaf extract of Leea indica may reduce inflammation, dissolve blood clots, and promote hair growth.

Wheat straw is valuable for its health benefits and various industrial uses.

Hair analysis can show nutritional status and environmental exposure, with phosphorus being very stable in hair and differences found based on gender and conditions like depression and autism.