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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Hair and wool have complex microscopic structures with microfibrils and varying cystine content.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Ruby laser pulses best destroy hair follicles during the growth phase and effectiveness varies with laser intensity; melanin is key for targeting, and timing treatments can improve results.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.

Diazoxide, minoxidil sulphate, and cromakalim relax rat blood vessels by opening K+ channels, with some differences in their actions.

White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Testosterone with or without finasteride doesn't improve thinking skills in older men with low testosterone.

Some treatments, like corticosteroids and sensitizing agents, can help with alopecia areata, but more high-quality research is needed.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

Folliculitis is an inflammation of hair follicles that requires proper diagnosis and treatment based on the specific cause.

Some psychiatric medications can cause hair loss, but it usually grows back after adjusting the medication.

Using dermoscopy to guide scalp biopsies is an effective way to diagnose cicatricial alopecia.

Finasteride effectively treats male pattern baldness, improving hair growth and density.

Caucasian women's hair appears thickest in their 20s, with perceived thinning after mid-30s due to both decreasing density and diameter.

Tight hairstyles and chemical relaxers can cause hair loss known as traction alopecia.