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The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.

Both individual and combined treatments of tofacitinib and corticosteroids can help regrow hair in moderate-to-severe alopecia areata, but ongoing treatment may be necessary.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

Mycophenolate mofetil may improve lupus nephritis remission more than cyclophosphamide but with uncertain safety.

Oral isotretinoin may slightly improve acne but increases the risk of side effects like dry lips and skin; more research is needed to understand its full risks and benefits.

Some antiseizure medications can cause cosmetic problems like hair loss, excessive hair growth, acne, and gum overgrowth.

Non-biologic immunosuppressive drugs are crucial for treating autoimmune and chronic inflammatory skin diseases.

A woman's new seizures were caused by a brain tumor likely linked to her past cancer treatment, and choosing safe seizure medications is important for women who can have children.

Low-dose oral minoxidil improves hair growth in male hair loss.

Abrocitinib at 100 mg and 200 mg daily may significantly improve moderate-to-severe atopic dermatitis in patients 12 years and older.

Finasteride 1 mg every other month works as well as daily dose for hair loss maintenance.

Oral minoxidil and topical minoxidil 5% both effectively improve female-pattern hair loss with safe side effects.

Finasteride 1.25 mg showed small improvements in hair density and thickness for female pattern hair loss, but more research is needed.

Combining platelet-rich plasma therapy with low dose oral minoxidil improved hair growth in men with hair loss, with slightly higher satisfaction at the higher minoxidil dose.

Taking 1mg of finasteride daily for hair loss can lower PSA levels by 40-50%, so to keep PSA effective as a cancer screening tool, the PSA value should be doubled during treatment.

Taking 1mg of finasteride daily can mildly improve metabolic health and glucose regulation in men with male pattern baldness.

Oral minoxidil effectively treats hair loss, with women needing lower doses (0.25 to 2.5 mg daily) and men needing higher doses (1.25 to 5 mg daily).

Combining low-dose dutasteride with finasteride improved a man's hair loss.

Increasing the dose of baricitinib to 4 mg helps more patients with severe alopecia areata regrow hair.

Low-dose oral minoxidil is effective and safe for treating hair loss in men and women.

Low dose oral minoxidil is generally safe and can improve hair loss in women, with some experiencing side effects and minimal blood pressure changes.

Low-dose oral minoxidil combined with topical minoxidil improves hair growth in breast cancer patients with therapy-induced hair loss.

Low dose finasteride causes only minor changes in PSA levels in men over 50 with BPH.

Low-dose oral minoxidil effectively treats female hair loss with good safety.

Vitamin B12 and aureomycin reduce the negative effects of high doses of cortisone in rats.